Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1991-5-8
|
pubmed:abstractText |
In developing countries, 5 to 8% of the space-occupying lesions of the central nervous system are tuberculomas. Diagnosis can be difficult in the absence of extracranial tuberculosis; computed tomography is suggestive only. To assess the value of brain biopsies in tuberculomas, the records of 15 patients aged 6 to 80 years were reviewed. Histological confirmation was obtained in 15 patients, and acid-fast bacilli were cultured from 12 patients. Intracranial hypertension was the principal sign in 11 patients; other neurological signs were related to the location of the tuberculoma. One patient had evidence of extracranial tuberculosis. Biopsy-related complications consisted of an epidural hematoma in 1 patient and hydrocephalus in another; both required additional surgery. One case of tuberculous meningitis was probably related to surgery and poor drug compliance. There was no postoperative mortality. Thirteen patients (2 were lost to follow-up) were cured after an average of 16 months of antituberculous therapy. It was concluded that the brain biopsy is useful in diagnosing tuberculoma but that there is some associated risk.
|
pubmed:commentsCorrections | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0148-396X
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
28
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
405-9
|
pubmed:dateRevised |
2004-11-17
|
pubmed:meshHeading |
pubmed-meshheading:1901395-Adolescent,
pubmed-meshheading:1901395-Adult,
pubmed-meshheading:1901395-Aged,
pubmed-meshheading:1901395-Aged, 80 and over,
pubmed-meshheading:1901395-Biopsy,
pubmed-meshheading:1901395-Brain Diseases,
pubmed-meshheading:1901395-Child,
pubmed-meshheading:1901395-Female,
pubmed-meshheading:1901395-Follow-Up Studies,
pubmed-meshheading:1901395-Humans,
pubmed-meshheading:1901395-Male,
pubmed-meshheading:1901395-Middle Aged,
pubmed-meshheading:1901395-Mycobacterium tuberculosis,
pubmed-meshheading:1901395-Reoperation,
pubmed-meshheading:1901395-Retrospective Studies,
pubmed-meshheading:1901395-Tomography, X-Ray Computed,
pubmed-meshheading:1901395-Tuberculoma,
pubmed-meshheading:1901395-Tuberculosis, Meningeal
|
pubmed:year |
1991
|
pubmed:articleTitle |
Brain biopsy in tuberculoma: the risks and benefits.
|
pubmed:affiliation |
Department of Medicine, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
|
pubmed:publicationType |
Journal Article
|