Linked Life Data

19013629

Source:http://linkedlifedata.com/resource/pubmed/id/19013629

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2009-2-10
pubmed:abstractText
Viruses have evolved to use cellular pathways to their advantage, including the ubiquitin-proteasome pathway of protein degradation. In several cases, viruses produce proteins that highjack cellular E3 ligases to modify their substrate specificity in order to eliminate unwanted cellular proteins, in particular inhibitors of the cell cycle. They can also inhibit E3 ligase to prevent specific protein degradation or even use the system to control the level of expression of their own proteins. In this review we explore the specific ways that small DNA tumor viruses exploit the ubiquitin-proteasome pathway for their own benefit.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1096-0341
pubmed:author
pubmed:issnType
Electronic
pubmed:day
20
pubmed:volume
384
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
317-23
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Manipulation of the ubiquitin-proteasome pathway by small DNA tumor viruses.
pubmed:affiliation
Department of Biochemistry, McGill University, Montreal, Canada.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't