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rdf:type |
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lifeskim:mentions |
umls-concept:C0017262,
umls-concept:C0185117,
umls-concept:C0681850,
umls-concept:C1550501,
umls-concept:C1706203,
umls-concept:C1979963,
umls-concept:C2003903,
umls-concept:C2243049,
umls-concept:C2349001,
umls-concept:C2697811,
umls-concept:C2911684
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pubmed:issue |
1-2
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pubmed:dateCreated |
2008-12-23
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pubmed:abstractText |
Circadian clocks regulate daily rhythms of behavior and physiology such as the sleep-wake cycle and hormonal secretion. Numerous characteristics of the behavioral and physiological processes change with age. In this study, we evaluated the circadian clockwork in older people by measuring daily profiles of PERIOD (PER) gene expression in peripheral blood mononuclear cells (PBMCs).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Cell Cycle Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Melatonin,
http://linkedlifedata.com/resource/pubmed/chemical/Nuclear Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/PER1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/PER2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/PER3 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Period Circadian Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factors
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0024-3205
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
2
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pubmed:volume |
84
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
33-7
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:19013183-Aged,
pubmed-meshheading:19013183-Aging,
pubmed-meshheading:19013183-Cell Cycle Proteins,
pubmed-meshheading:19013183-Circadian Rhythm,
pubmed-meshheading:19013183-Gene Expression Profiling,
pubmed-meshheading:19013183-Humans,
pubmed-meshheading:19013183-Leukocytes, Mononuclear,
pubmed-meshheading:19013183-Male,
pubmed-meshheading:19013183-Melatonin,
pubmed-meshheading:19013183-Middle Aged,
pubmed-meshheading:19013183-Nuclear Proteins,
pubmed-meshheading:19013183-Period Circadian Proteins,
pubmed-meshheading:19013183-RNA, Messenger,
pubmed-meshheading:19013183-Sleep,
pubmed-meshheading:19013183-Transcription Factors
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pubmed:year |
2009
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pubmed:articleTitle |
Expression profiles of PERIOD1, 2, and 3 in peripheral blood mononuclear cells from older subjects.
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pubmed:affiliation |
Department of Psychophysiology, National Institute of Mental Health, National Center of Neurology & Psychiatry, 4-1-1 Ogawa-Higashi, Kodaira, Tokyo 187-8553, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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