Linked Life Data

1901117

Source:http://linkedlifedata.com/resource/pubmed/id/1901117

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1991-5-2
pubmed:abstractText
Effect of GIK solution (50% glucose 100 ml + insulin 20IU + KCl 20 mEq) infused in an hour on the myocardial metabolism was studied in the postoperative period following the open-heart surgery. Increase of arterial glucose, pyruvate, K+ and PCO2 and the decrease of pH was significant at the end of infusion. Increase of coronary sinus blood PCO2, myocardial oxygen extraction ratio for glucose and carbohydrate and the decrease of pH was highly significant. Myocardial oxygen extraction ratio for carbohydrate correlated significantly with the increase of coronary sinus blood PCO2 and the decrease of pH. Although the cardiac index correlated poorly with the myocardial oxygen extraction ratio for carbohydrate, a significant correlation was observed between the coronary arterial-sinus blood K+ difference and the coronary sinus blood PCO2, pH and myocardial oxygen extraction ratio for carbohydrate. It is suggested that the infused glucose with insulin and K+ was metabolized and degraded to CO2 and H2O quickly in the TCA cycle producing ATP and the rest was stored as glycogen with the uptake of K+ in the myocardium.
pubmed:language
jpn
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0021-5252
pubmed:author
pubmed:issnType
Print
pubmed:volume
44
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
126-31
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
[Effect of GIK solution on the myocardial metabolism].
pubmed:affiliation
Department of Cardiovascular and Thoraic Surgery, Dokkyo University Koshigaya Hospital.
pubmed:publicationType
Journal Article, English Abstract