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pubmed-article:19005411pubmed:abstractTextMesenchymal stem cells (MSC) have multilineage differentiation and immunomodulatory capacities and are potentially useful for therapeutic applications, such as tissue regeneration and control of alloreactivity. MSC are present in most tissues including the transplantable organs. It is therefore unavoidable that MSC will be exposed to immunosuppressive drugs in a clinical transplantation setting. The molecular targets of these drugs are expressed in MSC, but the effect of their inhibition on MSC functioning is unknown.lld:pubmed
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pubmed-article:19005411pubmed:articleTitleSusceptibility of human mesenchymal stem cells to tacrolimus, mycophenolic acid, and rapamycin.lld:pubmed
pubmed-article:19005411pubmed:affiliationDepartment of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands. M.Hoogduijn@erasmusmc.nllld:pubmed
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