Source:http://linkedlifedata.com/resource/pubmed/id/19003768
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2008-11-12
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pubmed:abstractText |
Aspirin hypersensitivity syndrome includes several symptoms from the respiratory tract, skin and digestive system triggered by ingestion of aspirin or other nonsteroidal anti-inflammatory drugs. Asthmatic attacks precipitated by aspirin or other nonsteroidal anti-inflammatory drugs occur in about 10% of all asthmatic patients. In subjects with aspirin hypersensitivity disruption of synthesis of prostaglandin E2 (PGE2) and overproduction of cysteinyl leukotrienes (Cys-LT) seem to be crucial in the pathogenesis of bronchial symptoms. Double blind, placebo controlled challenges are regarded as a gold standard in the diagnosis of aspirin hypersensitivity.
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pubmed:language |
pol
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Allergens,
http://linkedlifedata.com/resource/pubmed/chemical/Anti-Inflammatory Agents...,
http://linkedlifedata.com/resource/pubmed/chemical/Aspirin,
http://linkedlifedata.com/resource/pubmed/chemical/Dinoprostone,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Leukotriene
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pubmed:status |
MEDLINE
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pubmed:issn |
0867-7077
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
76
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
366-77
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pubmed:meshHeading |
pubmed-meshheading:19003768-Allergens,
pubmed-meshheading:19003768-Anti-Inflammatory Agents, Non-Steroidal,
pubmed-meshheading:19003768-Aspirin,
pubmed-meshheading:19003768-Asthma,
pubmed-meshheading:19003768-Dinoprostone,
pubmed-meshheading:19003768-Drug Hypersensitivity,
pubmed-meshheading:19003768-Humans,
pubmed-meshheading:19003768-Receptors, Leukotriene
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pubmed:year |
2008
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pubmed:articleTitle |
[Aspirin and other nonsteroidal anti-inflammatory drugs hypersensitivity--mechanisms, diagnostics and treatment].
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pubmed:affiliation |
Klinika Chorób Wewnetrznych, Astmy i Alergii Uniwersytetu Medycznego w Lodzi Kierownik.
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pubmed:publicationType |
Journal Article,
English Abstract,
Review
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