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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2009-3-18
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pubmed:abstractText |
We showed previously that treatment with an agonistic anti-4-1BB Ab during the induction phase of murine experimental allergic conjunctivitis (EC) suppresses the development of this model disease. It was reported that 4-1BB promotes the expansion of regulatory T cells. Here we asked whether the suppression of EC by agonistic anti-4-1BB Ab treatment is mediated by regulatory T cells.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1423-0097
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2008 S. Karger AG, Basel.
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pubmed:issnType |
Electronic
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pubmed:volume |
148
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
305-10
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pubmed:meshHeading |
pubmed-meshheading:19001790-Ambrosia,
pubmed-meshheading:19001790-Animals,
pubmed-meshheading:19001790-Antibodies, Monoclonal,
pubmed-meshheading:19001790-Antigens, CD137,
pubmed-meshheading:19001790-CD8-Positive T-Lymphocytes,
pubmed-meshheading:19001790-Conjunctiva,
pubmed-meshheading:19001790-Conjunctivitis, Allergic,
pubmed-meshheading:19001790-Cytokines,
pubmed-meshheading:19001790-Disease Models, Animal,
pubmed-meshheading:19001790-Eosinophils,
pubmed-meshheading:19001790-Immunization,
pubmed-meshheading:19001790-Interleukin-2 Receptor alpha Subunit,
pubmed-meshheading:19001790-Mice,
pubmed-meshheading:19001790-Mice, Inbred BALB C,
pubmed-meshheading:19001790-Pollen,
pubmed-meshheading:19001790-Spleen,
pubmed-meshheading:19001790-T-Lymphocytes, Regulatory,
pubmed-meshheading:19001790-Thymectomy
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pubmed:year |
2009
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pubmed:articleTitle |
Regulatory T cells participate in 4-1BB-mediated suppression of experimental allergic conjunctivitis.
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pubmed:affiliation |
Department of Ophthalmology, Kochi Medical School, Kohasu Oko-cho, Nankoku City, Japan.
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pubmed:publicationType |
Journal Article
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