Linked Life Data

18988844

Source:http://linkedlifedata.com/resource/pubmed/id/18988844

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5903
pubmed:dateCreated
2008-11-7
pubmed:abstractText
The success of forward genetic (from phenotype to gene) approaches to uncover genes that drive the molecular mechanism of circadian clocks and control circadian behavior has been unprecedented. Links among genes, cells, neural circuits, and circadian behavior have been uncovered in the Drosophila and mammalian systems, demonstrating the feasibility of finding single genes that have major effects on behavior. Why was this approach so successful in the elucidation of circadian rhythms? This article explores the answers to this question and describes how the methods used successfully for identifying the molecular basis of circadian rhythms can be applied to other behaviors such as anxiety, addiction, and learning and memory.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1095-9203
pubmed:author
pubmed:issnType
Electronic
pubmed:day
7
pubmed:volume
322
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
909-12
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Searching for genes underlying behavior: lessons from circadian rhythms.
pubmed:affiliation
Howard Hughes Medical Institute, Northwestern University, Evanston, IL 60208, USA. j-takahashi@northwestern.edu
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural