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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2009-3-20
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pubmed:abstractText |
Intrahepatic cholestasis of pregnancy (ICP) has a complex aetiology with a significant genetic component. ABCB11 encodes the bile salt export pump (BSEP); mutations cause a spectrum of cholestatic disease, and are implicated in the aetiology of ICP.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1468-3288
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pubmed:author |
pubmed-author:ChambersJJ,
pubmed-author:DixonP HPH,
pubmed-author:GlantzAA,
pubmed-author:KeitelVV,
pubmed-author:KubitzRR,
pubmed-author:LammertFF,
pubmed-author:LintonK JKJ,
pubmed-author:MarschallH-UHU,
pubmed-author:MattssonL-ALA,
pubmed-author:MolokhiaMM,
pubmed-author:MooreG EGE,
pubmed-author:StrautnieksSS,
pubmed-author:ThompsonR JRJ,
pubmed-author:WilliamsonCC,
pubmed-author:van MilS W CSW
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pubmed:issnType |
Electronic
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pubmed:volume |
58
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
537-44
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pubmed:meshHeading |
pubmed-meshheading:18987030-ATP-Binding Cassette Transporters,
pubmed-meshheading:18987030-Case-Control Studies,
pubmed-meshheading:18987030-Cholestasis, Intrahepatic,
pubmed-meshheading:18987030-DNA Mutational Analysis,
pubmed-meshheading:18987030-Female,
pubmed-meshheading:18987030-Gene Frequency,
pubmed-meshheading:18987030-Genetic Predisposition to Disease,
pubmed-meshheading:18987030-Genotype,
pubmed-meshheading:18987030-Humans,
pubmed-meshheading:18987030-Models, Molecular,
pubmed-meshheading:18987030-Mutation,
pubmed-meshheading:18987030-Pregnancy,
pubmed-meshheading:18987030-Pregnancy Complications,
pubmed-meshheading:18987030-Structure-Activity Relationship
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pubmed:year |
2009
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pubmed:articleTitle |
Contribution of variant alleles of ABCB11 to susceptibility to intrahepatic cholestasis of pregnancy.
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pubmed:affiliation |
Maternal and Fetal Disease Group, Institute of Reproductive and Developmental Biology, Imperial College London, London, UK.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Multicenter Study
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