| pubmed-article:1898658 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1898658 | lifeskim:mentions | umls-concept:C0005953 | lld:lifeskim |
| pubmed-article:1898658 | lifeskim:mentions | umls-concept:C1512631 | lld:lifeskim |
| pubmed-article:1898658 | lifeskim:mentions | umls-concept:C0926407 | lld:lifeskim |
| pubmed-article:1898658 | lifeskim:mentions | umls-concept:C1171362 | lld:lifeskim |
| pubmed-article:1898658 | lifeskim:mentions | umls-concept:C0021038 | lld:lifeskim |
| pubmed-article:1898658 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:1898658 | lifeskim:mentions | umls-concept:C1515670 | lld:lifeskim |
| pubmed-article:1898658 | lifeskim:mentions | umls-concept:C0205148 | lld:lifeskim |
| pubmed-article:1898658 | lifeskim:mentions | umls-concept:C0591833 | lld:lifeskim |
| pubmed-article:1898658 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:1898658 | pubmed:dateCreated | 1991-2-1 | lld:pubmed |
| pubmed-article:1898658 | pubmed:abstractText | The membrane immunoglobulin heavy chain (micron) plays a feedback role during the pre-B stage of B lymphocyte differentiation. In pre-B cell lines, micron associates with two surrogate light chain proteins. The omega chain is disulfide linked to mu and was predicted to be the product of the lambda 5 gene. The iota chain is noncovalently associated with micron. We demonstrate that the omega protein is indeed the product of the lambda 5 gene and that mu, omega, and iota are coassociated in the same complex. Antibodies against the omega/lambda 5 protein demonstrate the existence of a subpopulation of "transitional" bone marrow B cells that express micron and omega on the cell surface. The majority of these cells also express surface kappa light chains, indicating that in B lymphoid ontogeny the lambda 5 gene is inactivated after the onset of kappa light chain expression. | lld:pubmed |
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| pubmed-article:1898658 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1898658 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1898658 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1898658 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:1898658 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1898658 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:1898658 | pubmed:issn | 0022-1007 | lld:pubmed |
| pubmed-article:1898658 | pubmed:author | pubmed-author:PillaiSS | lld:pubmed |
| pubmed-article:1898658 | pubmed:author | pubmed-author:CherayilB JBJ | lld:pubmed |
| pubmed-article:1898658 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1898658 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:1898658 | pubmed:volume | 173 | lld:pubmed |
| pubmed-article:1898658 | pubmed:geneSymbol | &lgr;5 | lld:pubmed |
| pubmed-article:1898658 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1898658 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1898658 | pubmed:pagination | 111-6 | lld:pubmed |
| pubmed-article:1898658 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:1898658 | pubmed:year | 1991 | lld:pubmed |
| pubmed-article:1898658 | pubmed:articleTitle | The omega/lambda 5 surrogate immunoglobulin light chain is expressed on the surface of transitional B lymphocytes in murine bone marrow. | lld:pubmed |
| pubmed-article:1898658 | pubmed:affiliation | Molecular Immunology Laboratory, Cancer Center of Massachusetts General Hospital, Boston. | lld:pubmed |
| pubmed-article:1898658 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1898658 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:1898658 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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