18982010

Source:http://linkedlifedata.com/resource/pubmed/id/18982010

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0001811, umls-concept:C0016126, umls-concept:C0017428, umls-concept:C0028754
pubmed:issue	12
pubmed:dateCreated	2008-12-16
pubmed:abstractText	Aging is associated with increased visceral fat, and recent studies suggested that in turn, visceral fat could influence longevity. We therefore tested whether obesity could be a condition of premature aging. Whole-genome microarray analysis of gene expression between obese mice, aged mice and their respective controls, revealed that long-term adaptations in gene expression in visceral fat upon aging are different from those occurring during fat accretion in young adult animals, suggesting specific, divergent and non overlapping pathways of regulation.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/101256108
pubmed:citationSubset	IM
pubmed:status	MEDLINE
pubmed:month	Dec
pubmed:issn	1476-5497
pubmed:author	pubmed-author:MiaraPP, pubmed-author:PicardFF
pubmed:issnType	Electronic
pubmed:volume	32
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	1873-4
pubmed:meshHeading	pubmed-meshheading:18982010-Aging, pubmed-meshheading:18982010-Animals, pubmed-meshheading:18982010-Gene Expression, pubmed-meshheading:18982010-Intra-Abdominal Fat, pubmed-meshheading:18982010-Male, pubmed-meshheading:18982010-Mice, pubmed-meshheading:18982010-Mice, Obese, pubmed-meshheading:18982010-Obesity
pubmed:year	2008
pubmed:articleTitle	Obesity and aging have divergent genomic fingerprints.
pubmed:affiliation	Laval Hospital Research Center and Faculty of Pharmacy, Laval University, Québec, QC, Canada.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't