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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2009-1-22
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pubmed:abstractText |
The insulin-like growth factor binding protein 7 (IGFBP7) gene is regulated by DNA methylation in colon cancer, which was identified in our previous study. In this study, we examined the effects of DNA methylation inhibitor 5-aza-2'-deoxycytidine (5-aza-dC) on IGFBP7 reactivation and cell biological behaviors in vitro to investigate a potential role for 5-aza-dC in treating colorectal cancer.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1555-8576
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1896-900
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pubmed:meshHeading |
pubmed-meshheading:18981723-Azacitidine,
pubmed-meshheading:18981723-Cell Cycle,
pubmed-meshheading:18981723-Cell Division,
pubmed-meshheading:18981723-Cell Line, Tumor,
pubmed-meshheading:18981723-Cell Movement,
pubmed-meshheading:18981723-Colonic Neoplasms,
pubmed-meshheading:18981723-DNA,
pubmed-meshheading:18981723-DNA Methylation,
pubmed-meshheading:18981723-G1 Phase,
pubmed-meshheading:18981723-Humans,
pubmed-meshheading:18981723-Insulin-Like Growth Factor Binding Proteins,
pubmed-meshheading:18981723-Neoplasm Invasiveness,
pubmed-meshheading:18981723-RNA, Messenger,
pubmed-meshheading:18981723-Transcription, Genetic
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pubmed:year |
2008
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pubmed:articleTitle |
Reactivation of IGFBP7 by DNA demethylation inhibits human colon cancer cell growth in vitro.
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pubmed:affiliation |
Department of Pathology, School of Medicine, Zhejiang University, Hangzhou, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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