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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2009-1-19
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pubmed:abstractText |
Levodopa induced dyskinesias (LID) are a common problem which ultimately limit the effective treatment of patients with Parkinson's disease (PD). There is accumulating evidence that LID develop due to abnormal synaptic plasticity, which is in turn influenced by the release of brain derived neurotrophic factor (BDNF).
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1468-330X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
80
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
141-4
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:18977816-Adult,
pubmed-meshheading:18977816-Aged,
pubmed-meshheading:18977816-Alleles,
pubmed-meshheading:18977816-Antiparkinson Agents,
pubmed-meshheading:18977816-Brain-Derived Neurotrophic Factor,
pubmed-meshheading:18977816-Corpus Striatum,
pubmed-meshheading:18977816-Dyskinesia, Drug-Induced,
pubmed-meshheading:18977816-Female,
pubmed-meshheading:18977816-Gene Expression,
pubmed-meshheading:18977816-Genotype,
pubmed-meshheading:18977816-Humans,
pubmed-meshheading:18977816-Levodopa,
pubmed-meshheading:18977816-Male,
pubmed-meshheading:18977816-Middle Aged,
pubmed-meshheading:18977816-Neuronal Plasticity,
pubmed-meshheading:18977816-Parkinson Disease,
pubmed-meshheading:18977816-Polymorphism, Genetic,
pubmed-meshheading:18977816-Receptor, trkB,
pubmed-meshheading:18977816-Risk Factors,
pubmed-meshheading:18977816-Synapses,
pubmed-meshheading:18977816-Time Factors
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pubmed:year |
2009
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pubmed:articleTitle |
BDNF val66met influences time to onset of levodopa induced dyskinesia in Parkinson's disease.
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pubmed:affiliation |
Cambridge Centre for Brain Repair, Cambridge, UK. T.Foltynie@ion.ucl.ac.uk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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