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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2009-4-17
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pubmed:abstractText |
In the general population, folic acid supplementation during pregnancy has been demonstrated to reduce the frequency of neural tube defects (NTDs) and other major congenital malformations (MCMs). It is recommended that women with epilepsy contemplating pregnancy take supplemental folic acid because of the known antifolate effect of some antiepileptic drugs (AEDs). Here the aim was to determine the effectiveness of this practice.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1468-330X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
80
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
506-11
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pubmed:meshHeading |
pubmed-meshheading:18977812-Abnormalities, Drug-Induced,
pubmed-meshheading:18977812-Adult,
pubmed-meshheading:18977812-Cleft Palate,
pubmed-meshheading:18977812-Dietary Supplements,
pubmed-meshheading:18977812-Drug Utilization,
pubmed-meshheading:18977812-Epilepsy,
pubmed-meshheading:18977812-Female,
pubmed-meshheading:18977812-Folic Acid,
pubmed-meshheading:18977812-Follow-Up Studies,
pubmed-meshheading:18977812-Great Britain,
pubmed-meshheading:18977812-Guidelines as Topic,
pubmed-meshheading:18977812-Heart Defects, Congenital,
pubmed-meshheading:18977812-Humans,
pubmed-meshheading:18977812-Hypospadias,
pubmed-meshheading:18977812-Infant, Newborn,
pubmed-meshheading:18977812-Male,
pubmed-meshheading:18977812-Neural Tube Defects,
pubmed-meshheading:18977812-Pregnancy,
pubmed-meshheading:18977812-Prospective Studies,
pubmed-meshheading:18977812-Registries,
pubmed-meshheading:18977812-Vitamins,
pubmed-meshheading:18977812-Young Adult
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pubmed:year |
2009
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pubmed:articleTitle |
Folic acid use and major congenital malformations in offspring of women with epilepsy: a prospective study from the UK Epilepsy and Pregnancy Register.
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pubmed:affiliation |
Department of Neurology, Royal Group of Hospitals, Belfast, UK. jim.morrow@belfasttrust.hscni.net
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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