rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
11
|
pubmed:dateCreated |
2008-11-10
|
pubmed:abstractText |
Repeated injection of streptococcal cell wall (SCW) fragments results in chronic arthritis in mice. The objective of this study was to identify genes and pathways that determine disease progression based on gene expression profiling in this model.
|
pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
0004-3591
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
58
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
3471-84
|
pubmed:meshHeading |
pubmed-meshheading:18975327-Acute Disease,
pubmed-meshheading:18975327-Animals,
pubmed-meshheading:18975327-Arthritis, Experimental,
pubmed-meshheading:18975327-Biological Markers,
pubmed-meshheading:18975327-Chronic Disease,
pubmed-meshheading:18975327-Down-Regulation,
pubmed-meshheading:18975327-Gene Expression,
pubmed-meshheading:18975327-Interleukin-12 Subunit p40,
pubmed-meshheading:18975327-Interleukin-17,
pubmed-meshheading:18975327-Macrophage Activation,
pubmed-meshheading:18975327-Male,
pubmed-meshheading:18975327-Mice,
pubmed-meshheading:18975327-Mice, Inbred C57BL,
pubmed-meshheading:18975327-Nitric Oxide Synthase Type II,
pubmed-meshheading:18975327-Oxidation-Reduction,
pubmed-meshheading:18975327-Reverse Transcriptase Polymerase Chain Reaction
|
pubmed:year |
2008
|
pubmed:articleTitle |
The molecular signature of oxidative metabolism and the mode of macrophage activation determine the shift from acute to chronic disease in experimental arthritis: critical role of interleukin-12p40.
|
pubmed:affiliation |
Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands. N.Takahashi@reuma.umcn.nl
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|