Source:http://linkedlifedata.com/resource/pubmed/id/18974006
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
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pubmed:dateCreated |
2008-11-10
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pubmed:abstractText |
The anterior cingulate cortex (ACC) is implicated in neuropsychiatric disorders. Post-mortem axon bundle data will be important to complement novel MRI methods for analysing cortical diffusion data. [Jespersen SN, Kroenke CD, Ostergaard L, et al. Modeling dendrite density from magnetic resonance diffusion measurements. Neuroimage. 2007;34:1473-86] Therefore we aimed to assess perimeter, area, density and spacing of axon bundles in BA24 not previously measured in the human ACC using image analysis of 10 microm-thick tangential sections of layer IV in 4 normal patients. Axon bundle mean perimeter was 53.8 microm, mean area was 197.1 microm(2), mean density was 226.3/mm(2), and mean spacing was 73.8 microm. Thus, axon bundles were widely spaced relative to cell body minicolumns and other prelimbic areas. A review of the literature suggests that there is hierarchical regional variation of bundle and column spacing.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0967-5868
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1389-92
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pubmed:meshHeading |
pubmed-meshheading:18974006-Aged, 80 and over,
pubmed-meshheading:18974006-Axons,
pubmed-meshheading:18974006-Brain Mapping,
pubmed-meshheading:18974006-Female,
pubmed-meshheading:18974006-Gyrus Cinguli,
pubmed-meshheading:18974006-Humans,
pubmed-meshheading:18974006-Magnetic Resonance Imaging,
pubmed-meshheading:18974006-Male,
pubmed-meshheading:18974006-Neuroglia,
pubmed-meshheading:18974006-Postmortem Changes
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pubmed:year |
2008
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pubmed:articleTitle |
Axon bundle spacing in the anterior cingulate cortex of the human brain.
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pubmed:affiliation |
Dipartimento di Neuroscienze, Scienze Psichiatriche e Anestesiologiche, Universitá di Messina, Italy.
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pubmed:publicationType |
Journal Article
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