Source:http://linkedlifedata.com/resource/pubmed/id/18972548
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
2009-2-2
|
pubmed:abstractText |
Amyotrophic lateral sclerosis and Parkinsonism-dementia complex of the Kii peninsula (Kii ALS/PDC) is an endemic and a tauopathy, which shows clinical symptoms of amyotrophy, parkinsonism, and dementia. The objective of this study was to report the role of oxidative stress on Kii ALS/PDC using biochemical analysis. Urinary 8-hydroxydeoxyguanosine (8-OHdG)/creatinine ratio was analyzed in 11 patients with Kii ALS/PDC and 8 normal controls. The mean level of urinary 8-OHdG/creatinine ratio of the patients with Kii ALS/PDC was significantly higher than that of control subjects. Oxidative stress may be implicated in pathogenesis of Kii ALS/PDC.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
|
pubmed:issn |
1531-8257
|
pubmed:author | |
pubmed:issnType |
Electronic
|
pubmed:day |
15
|
pubmed:volume |
24
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
123-6
|
pubmed:meshHeading |
pubmed-meshheading:18972548-Aged,
pubmed-meshheading:18972548-Aged, 80 and over,
pubmed-meshheading:18972548-Amyotrophic Lateral Sclerosis,
pubmed-meshheading:18972548-Creatinine,
pubmed-meshheading:18972548-Endemic Diseases,
pubmed-meshheading:18972548-Female,
pubmed-meshheading:18972548-Guanosine,
pubmed-meshheading:18972548-Humans,
pubmed-meshheading:18972548-Japan,
pubmed-meshheading:18972548-Male,
pubmed-meshheading:18972548-Oxidative Stress,
pubmed-meshheading:18972548-Parkinsonian Disorders,
pubmed-meshheading:18972548-Severity of Illness Index,
pubmed-meshheading:18972548-Tauopathies
|
pubmed:year |
2009
|
pubmed:articleTitle |
Increased oxidative stress in patients with amyotrophic lateral sclerosis/Parkinsonism-dementia complex in the Kii peninsula, Japan.
|
pubmed:affiliation |
Department of Neurology, Mie University School of Medicine, Tsu, Japan.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|