Linked Life Data

1897139

Source:http://linkedlifedata.com/resource/pubmed/id/1897139

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1991-10-23
pubmed:abstractText
In six patients with selected inflammatory rheumatic diseases the authors found increased numbers of LGL in the peripheral blood. Concurrently in these patients an increase of lymphocytes with the CD57 sign was found. In one patient with rheumatoid arthritis more detailed analysis revealed a reduced number of lymphocytes with sign CD16. In this patient in the peripheral blood cells with signs CD3+ and CD57 were found and the function of NK cells was markedly reduced. The clinical course of the disease in the patients was severe, in particular in SLE, where in three patients the disease was associated with the development of lupus glomerulonephritis. The patients were treated by immunosuppressive therapy. The authors reflect on the causes of the increase of LGL cells and do not rule out the possible presence of a serious immunoregulatory disorder between T and B lymphocytes.
pubmed:language
slo
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0042-773X
pubmed:author
pubmed:issnType
Print
pubmed:volume
37
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
572-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
[Increased numbers of large granular lymphocytes in the peripheral blood in selected inflammatory rheumatic diseases].
pubmed:affiliation
Výskumný ústav reumatických chorôb, Piestany.
pubmed:publicationType
Journal Article, English Abstract