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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2008-11-18
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pubmed:abstractText |
Parasite-based diagnosis of malaria by microscopy requires laboratory skills that are generally unavailable at peripheral health facilities. Rapid diagnostic tests (RDTs) require less expertise, but accuracy under operational conditions has not been fully evaluated in Uganda. There are also concerns about RDTs that use the antigen histidine-rich protein 2 (HRP2) to detect Plasmodium falciparum, because this antigen can persist after effective treatment, giving false positive test results in the absence of infection. An assessment of the accuracy of Malaria Pf immuno-chromatographic test (ICT) and description of persistent antigenicity of HRP2 RDTs was undertaken in a hyperendemic area of Uganda.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1475-2875
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
221
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:18959777-Adolescent,
pubmed-meshheading:18959777-Adult,
pubmed-meshheading:18959777-Animals,
pubmed-meshheading:18959777-Antigens, Protozoan,
pubmed-meshheading:18959777-Child,
pubmed-meshheading:18959777-Child, Preschool,
pubmed-meshheading:18959777-Cross-Sectional Studies,
pubmed-meshheading:18959777-Diagnostic Tests, Routine,
pubmed-meshheading:18959777-Endemic Diseases,
pubmed-meshheading:18959777-Female,
pubmed-meshheading:18959777-Humans,
pubmed-meshheading:18959777-Infant,
pubmed-meshheading:18959777-Malaria, Falciparum,
pubmed-meshheading:18959777-Male,
pubmed-meshheading:18959777-Microscopy,
pubmed-meshheading:18959777-Observer Variation,
pubmed-meshheading:18959777-Plasmodium falciparum,
pubmed-meshheading:18959777-Predictive Value of Tests,
pubmed-meshheading:18959777-Protozoan Proteins,
pubmed-meshheading:18959777-Sensitivity and Specificity,
pubmed-meshheading:18959777-Uganda
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pubmed:year |
2008
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pubmed:articleTitle |
Operational accuracy and comparative persistent antigenicity of HRP2 rapid diagnostic tests for Plasmodium falciparum malaria in a hyperendemic region of Uganda.
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pubmed:affiliation |
Malaria Consortium Africa, Plot 2, Sturrock Road, P O Box 8045, Kampala, Uganda. d.kyabayinze@malariaconsortium.org
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't,
Evaluation Studies
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