Linked Life Data

18952697

Source:http://linkedlifedata.com/resource/pubmed/id/18952697

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2009-3-23
pubmed:abstractText
Anti-neutrophil cytoplasmic antibodies (ANCA) against proteinase 3 (PR3) are postulated to injure vascular endothelium by inducing cytokine-primed neutrophils to release proteolytic enzymes and generate reactive oxygen species. Anti-PR3 induce exocytosis, and since priming is associated with upregulation of plasma membrane proteins by exocytosis of intracellular granules, we tested the hypothesis that anti-PR3 prime neutrophils in the absence of cytokines.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1460-2385
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
24
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1150-7
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Anti-proteinase 3 antibodies both stimulate and prime human neutrophils.
pubmed:affiliation
Department of Medicine, University of Louisville, 615 S. Preston Street, Louisville, KY 40202-1718, USA.
pubmed:publicationType
Journal Article