Linked Life Data

18951331

Source:http://linkedlifedata.com/resource/pubmed/id/18951331

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2008-10-27
pubmed:abstractText
Controlled expression of matrix metalloproteinase-9 (MMP9) is vital for normal uterine physiology, whereas abnormal expression of MMP9 is associated with uterine disease. Despite the importance of MMP9 within the uterus, its regulation is poorly understood. In this review, the complex regulation of MMP9 within the uterus is highlighted, and the potential novel role of microRNAs in the regulation of this protease is discussed. Emphasis is placed on the necessity to enhance our understanding of the regulation of MMP9 expression, which may lead to the establishment of novel approaches to counteract misexpression of this protease and the diseases associated with it.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1526-4564
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
26
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
494-9
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Regulation of uterine matrix metalloproteinase-9 and the role of microRNAs.
pubmed:affiliation
Departments of Obstetrics & Gynecology and Molecular & Integrative Physiology, University of Kansas Medical Center, Kansas City, Kansas 66160, USA. wnothnic@kumc.edu
pubmed:publicationType
Journal Article, Review, Research Support, N.I.H., Extramural