Linked Life Data

18946475

Source:http://linkedlifedata.com/resource/pubmed/id/18946475

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
2008-10-23
pubmed:abstractText
Cell polarity relies on the asymmetric organization of cellular components and structures. Actin and microtubules are well suited to provide the structural basis for cell polarization because of their inherent structural polarity along the polymer lattices and intrinsic dynamics that allow them to respond rapidly to polarity cues. In general, the actin cytoskeleton drives the symmetry-breaking process that enables the establishment of a polarized distribution of regulatory molecules, whereas microtubules build on this asymmetry and maintain the stability of the polarized organization. Crosstalk coordinates the functions of the two cytoskeletal systems.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1471-0080
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
860-73
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Beyond polymer polarity: how the cytoskeleton builds a polarized cell.
pubmed:affiliation
The Stowers Institute for Medical Research, 1000 East 50th Street, Kansas City, Missouri 64110, USA. rli@stowers-institute.org
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't