Linked Life Data

18942368

Source:http://linkedlifedata.com/resource/pubmed/id/18942368

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2008-10-23
pubmed:abstractText
This study was devoted to the evaluation of morphofunctional alterations in the pancreas in the conditions of physiological and premature aging using the experimental model of irradiation-induced aging, and the possibility of peptidergic regulation of age-related alterations in the pancreas was also studied. Age-related alterations in the pancreas of old animals in the conditions of physiological aging were revealed in the form of dystrophic alterations of main cell populations, disordered microcirculatory vascular channels and reduced level of physiological regeneration of this organ. In the conditions of irradiation-induced premature aging the above mentioned manifestations of dystrophic alterations in the pancreas tissue were found to be more pronounced. Administration of tripeptide T-38 (Lys-Glu-Asp) to old irradiated animals activated the processes of post-irradiation reparative regeneration, thus restoring the disordered endocrine homeostasis in the pancreas.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1561-9125
pubmed:author
pubmed:issnType
Print
pubmed:volume
21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
240-5
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
[Peptidergic regulation of the pancreas function in the experimental model of rats with accelerated aging].
pubmed:publicationType
Journal Article, English Abstract