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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2008-10-20
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pubmed:abstractText |
Substance P (SP) is a vasodilator that may contribute to systemic and splanchnic vasodilatation in cirrhosis. The aim of this study was to determine the effects of SP (dose--13 pg/kg) and its specific inhibitor, RP67580 (dose--300 microg/kg) on mean arterial pressure (MAP) and portal pressure (PP) in cirrhotic rats and controls.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0036-5521
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
43
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
328-33
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pubmed:meshHeading |
pubmed-meshheading:18938661-Analgesics,
pubmed-meshheading:18938661-Anesthesia,
pubmed-meshheading:18938661-Animals,
pubmed-meshheading:18938661-Biopsy,
pubmed-meshheading:18938661-Blood Flow Velocity,
pubmed-meshheading:18938661-Carbon Tetrachloride,
pubmed-meshheading:18938661-Dose-Response Relationship, Drug,
pubmed-meshheading:18938661-Humans,
pubmed-meshheading:18938661-Isoindoles,
pubmed-meshheading:18938661-Liver Circulation,
pubmed-meshheading:18938661-Liver Cirrhosis, Experimental,
pubmed-meshheading:18938661-Neurotransmitter Agents,
pubmed-meshheading:18938661-Rats,
pubmed-meshheading:18938661-Rats, Sprague-Dawley,
pubmed-meshheading:18938661-Receptors, Neurokinin-1,
pubmed-meshheading:18938661-Substance P,
pubmed-meshheading:18938661-Treatment Outcome
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pubmed:year |
2008
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pubmed:articleTitle |
Hemodynamic effects of substance P and its receptor antagonist RP67580 in anesthetized rats with carbon tetrachloride-induced cirrhosis.
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pubmed:affiliation |
Liver Center, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA. acardena@clinic.ub.es
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pubmed:publicationType |
Journal Article,
Comparative Study
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