Linked Life Data

18937559

Source:http://linkedlifedata.com/resource/pubmed/id/18937559

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2008-10-21
pubmed:abstractText
Chronic obstructive pulmonary disease (COPD) is an inflammatory disease characterized by the progressive deterioration of pulmonary function and irreversible airway obstruction. Investigations of the molecular pathogenesis of COPD have not yet provided complete answers to the mechanisms that determine the onset and progression of this illness. Therefore, therapeutic choices are limited and new strategies are needed to prevent, manage and treat this disorder. In particular, the application of complementary approaches, including gel- and liquid chromatography mass spectrometry-based proteomic techniques on sputum and/or bronchoalveolar lavage may provide a better understanding of the proteome differentially expressed by COPD patients in the course of the disease. The identification of appropriate and reliable biomarkers is, thus, an essential step for the diagnostics and treatment of these patients.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1744-8387
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
693-704
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Proteomics-based diagnosis of chronic obstructive pulmonary disease: the hunt for new markers.
pubmed:affiliation
Functional Genomics Group, BioAnalytical Science Department, Nestlé Research Center, Nestec Ltd, Vers-chez-les-Blanc, 1000 Lausanne 26, Switzerland. begona.casado@rdls.nestle.com
pubmed:publicationType
Journal Article, Review