Linked Life Data

18937011

Source:http://linkedlifedata.com/resource/pubmed/id/18937011

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
2008-11-5
pubmed:abstractText
Leukamenin E, an ent-kaurene diterpenoid isolated from Isodon racemosa (Hemsl) Hara, showed phytotoxic effects on root growth and root hair development of lettuce seedlings (Lactuca sativa L.). Lower concentrations (10 microM) of leukamenin E did not affect root growth, but at concentrations higher than 50 microM, the rate was inhibited. The influence of leukamenin E on root growth rate was closely correlated with alterations in the mitotic index. A low incidence of aberrant mitosis image was observed when lettuce roots were treated with higher concentrations (100 and 200 microM) of leukamenin E. This suggests that inhibition of root growth may be due to inhibition of cell division. All tested concentrations of the diterpenoid (10 microM or more) inhibited root hair development in a dose-dependent manner. At a concentration of 80 microM, leukamenin E completely blocked root hair initiation. Application of Ag(+)-an ethylene action inhibitor-to lettuce seedlings inhibited root hair elongation similar to the diterpenoid. Enhanced root hair length was stimulated by exogenous ethephon-an ethylene-releasing agent-and could be reversed by addition of leukamenin E. This suggests that leukamenin E may act as a potential ethylene action antagonist in the inhibition of lettuce root hair development. We conclude that leukamenin E may curb root hair development by interfering with ethylene action at concentrations above 10 microM and inhibits root growth via inhibition of cell division at concentrations above 50 microM.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0098-0331
pubmed:author
pubmed:issnType
Print
pubmed:volume
34
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1492-500
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Phytotoxic effects of leukamenin E (an ent-kaurene diterpenoid) on root growth and root hair development in Lactuca sativa L. seedlings.
pubmed:affiliation
College of Life Sciences, Northwest Normal University, Lanzhou 730070, People's Republic of China. dinglan@nwnu.edu.cn
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't