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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
20
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pubmed:dateCreated |
2008-10-17
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pubmed:abstractText |
Severe acute radiation dermatitis is observed in approximately 5% to 10% of patients who receive whole-breast radiotherapy. Several factors, including treatment-related and patient-oriented factors, are involved in susceptibility to severe dermatitis. Genetic factors are also thought to be related to a patient's susceptibility to severe dermatitis. To elucidate genetic polymorphisms associated with a susceptibility to radiation-induced dermatitis, a large-scale single-nucleotide polymorphism (SNP) analysis using DNA samples from 156 patients with breast cancer was conducted.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1078-0432
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pubmed:author |
pubmed-author:AkimotoTetsuoT,
pubmed-author:AokiMasahikoM,
pubmed-author:HareyamaMasatoM,
pubmed-author:HiraokaMasahiroM,
pubmed-author:HirokawaYutakaY,
pubmed-author:IsomuraMinoruM,
pubmed-author:KaneyasuYukoY,
pubmed-author:KarasawaKumikoK,
pubmed-author:MikiYoshioY,
pubmed-author:MitsuhashiNorioN,
pubmed-author:NataleW KWK,
pubmed-author:NishimuraYasumasaY,
pubmed-author:NodaTetsuoT,
pubmed-author:SaiHeitetsuH,
pubmed-author:SakataKoh-IchiK,
pubmed-author:SugitaTadasiT,
pubmed-author:TachiiriSeijiS,
pubmed-author:TomidaAkihiroA,
pubmed-author:TsuruoTakashiT,
pubmed-author:YamashitaTakashiT
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pubmed:issnType |
Print
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pubmed:day |
15
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|
pubmed:volume |
14
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|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
6683-9
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pubmed:meshHeading |
pubmed-meshheading:18927311-ATP-Binding Cassette Transporters,
pubmed-meshheading:18927311-Adult,
pubmed-meshheading:18927311-Aged,
pubmed-meshheading:18927311-Breast Neoplasms,
pubmed-meshheading:18927311-Case-Control Studies,
pubmed-meshheading:18927311-Female,
pubmed-meshheading:18927311-Genetic Predisposition to Disease,
pubmed-meshheading:18927311-Humans,
pubmed-meshheading:18927311-Middle Aged,
pubmed-meshheading:18927311-Polymorphism, Single Nucleotide,
pubmed-meshheading:18927311-Prognosis,
pubmed-meshheading:18927311-Radiodermatitis,
pubmed-meshheading:18927311-Receptors, Interleukin-12,
pubmed-meshheading:18927311-Risk Factors
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pubmed:year |
2008
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pubmed:articleTitle |
IL12RB2 and ABCA1 genes are associated with susceptibility to radiation dermatitis.
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pubmed:affiliation |
Genome Center, Japanese Foundation for Cancer Research, Japan.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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