Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2009-8-3
pubmed:abstractText
Although measuring health-related quality of life (HRQoL) in adolescents with cancer helps clinicians to personalize care for their patients, no previous studies have included HRQoL measurement at the time of diagnosis of osteosarcoma (OS) or acute myeloid leukemia (AML). The purpose of this study was to evaluate the feasibility of measuring adolescents' HRQoL at the time of their diagnosis of OS or AML, and to compare their ratings with those of their parents and of similarly diagnosed but younger patients aged 8-12 years. Participants included 126 patients (79 adolescents) and 130 parents (78 parents of adolescents); most completed the HRQoL instrument/s within 48 h of the first chemotherapy cycle. Ninety-three percent of adolescents diagnosed with OS and 93% of those diagnosed with AML completed the HRQoL instruments. Agreement between the adolescents and their parents ranged from 0.29 to 0.71 (OS) and 0.44 to 0.62 (AML). In all domains, OS adolescents had significantly lower PedsQL v.4.0 scores than adolescents with AML. Our findings demonstrates the feasibility of measuring HRQoL in adolescents with OS or AML (and their parents) at the time of diagnosis, and thus their HRQoL ratings can be used to inform their cancer care from diagnosis forward.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1532-2122
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
156-63
pubmed:meshHeading
pubmed-meshheading:18926773-Adaptation, Psychological, pubmed-meshheading:18926773-Adolescent, pubmed-meshheading:18926773-Age Factors, pubmed-meshheading:18926773-Analysis of Variance, pubmed-meshheading:18926773-Antineoplastic Combined Chemotherapy Protocols, pubmed-meshheading:18926773-Child, pubmed-meshheading:18926773-Cohort Studies, pubmed-meshheading:18926773-Early Detection of Cancer, pubmed-meshheading:18926773-Female, pubmed-meshheading:18926773-Humans, pubmed-meshheading:18926773-Leukemia, Myeloid, Acute, pubmed-meshheading:18926773-Male, pubmed-meshheading:18926773-Osteosarcoma, pubmed-meshheading:18926773-Parents, pubmed-meshheading:18926773-Probability, pubmed-meshheading:18926773-Psychometrics, pubmed-meshheading:18926773-Quality of Life, pubmed-meshheading:18926773-Questionnaires, pubmed-meshheading:18926773-Sex Factors, pubmed-meshheading:18926773-Sickness Impact Profile, pubmed-meshheading:18926773-Time Factors
pubmed:year
2009
pubmed:articleTitle
Health-related quality of life in adolescents at the time of diagnosis with osteosarcoma or acute myeloid leukemia.
pubmed:affiliation
Division of Nursing Research, St. Jude Children's Research Hospital, Memphis, TN 38105, USA. pam.hinds@stjude.org
pubmed:publicationType
Journal Article, Comparative Study