Source:http://linkedlifedata.com/resource/pubmed/id/18926757
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6 Pt 1
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pubmed:dateCreated |
2008-12-8
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pubmed:abstractText |
Diabetic nephropathy is the leading cause of end-stage kidney disease in developed countries and is related to chronic hyperglycaemia. The increased production and tissue deposition of advanced glycation end products (AGE) are known to play a major role in the pathogenesis of diabetic kidney damage. This study was undertaken to determine if lysozyme (LZ), microencapsulated in orally administrable chitosan-coated alginate microspheres (MS), is effective against the early changes seen in the initial stages of diabetic nephropathy.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1262-3636
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
34
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
587-94
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pubmed:meshHeading |
pubmed-meshheading:18926757-Albuminuria,
pubmed-meshheading:18926757-Animals,
pubmed-meshheading:18926757-Blood Glucose,
pubmed-meshheading:18926757-Body Weight,
pubmed-meshheading:18926757-Capsules,
pubmed-meshheading:18926757-Diabetes Mellitus, Experimental,
pubmed-meshheading:18926757-Diabetic Nephropathies,
pubmed-meshheading:18926757-Glycosuria,
pubmed-meshheading:18926757-Glycosylation End Products, Advanced,
pubmed-meshheading:18926757-Muramidase,
pubmed-meshheading:18926757-Rats,
pubmed-meshheading:18926757-Rats, Wistar
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pubmed:year |
2008
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pubmed:articleTitle |
Orally administered microencapsulated lysozyme downregulates serum AGE and reduces the severity of early-stage diabetic nephropathy.
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pubmed:affiliation |
Callerio Foundation-Onlus, Institutes of Biological Researches, via Alexander Fleming 22631, 34127 Trieste, Italy. m.cocchietto@callerio.org
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pubmed:publicationType |
Journal Article
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