Source:http://linkedlifedata.com/resource/pubmed/id/18926644
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
7-8
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| pubmed:dateCreated |
2008-12-2
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| pubmed:abstractText |
The aim of the study was to show the emergence of the qnr genes in extended spectrum beta-lactamases producing enterobacteria in Abidjan between 2005 and 2006. The whole of 151 strains of extended spectrum beta-lactamases producing enterobacteria were studied: 64 Escherichia coli, 66 Klebsiella pneumoniae, seven Klebsiella oxytoca and 14 Enterobacter spp. isolated from various biological products and from in- and out-patients. The techniques of disks diffusion, double-disk synergy, E-test were respectively used for the antimicrobial susceptibility test, the detection of extended spectrum beta-lactamases and the minimal inhibiting concentration. The bla genes(SHV, TEM, CTXM groups 1, 2, 8, 9), and AmpC were determined by PCR and characterized by sequencing. A global prevalence of 27,2 % (41/151) and rates of 9,9, 14,6, 2,7 % for the qnr genes A, B, A and S were observed. The distribution was 42,9 % for Enterobacter spp, 31,2 % for Escherichia coli, 20,5 % for Klebsiella; 30 strains expressed at least two bla genes; four strains were associated with AmpC. The strains were resistant to the cotrimoxazole (97,6 %), to the céfépime (73,2 %), to the céfoxitine (56,1 %), to the imipénème (0 %) and 43,9 % to all the aminosides. This high qnr gene prevalence associated with several types of bla genes in epidemic matter, the high level of resistance to antibiotics make fear a high risk of the transmission of multi-resistants bacteria and challenge the authorities for a resistance monitoring policy.
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| pubmed:language |
fre
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
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| pubmed:issn |
0369-8114
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| pubmed:author | |
| pubmed:issnType |
Print
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| pubmed:volume |
56
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
439-46
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| pubmed:meshHeading |
pubmed-meshheading:18926644-Bacterial Proteins,
pubmed-meshheading:18926644-Body Fluids,
pubmed-meshheading:18926644-Community-Acquired Infections,
pubmed-meshheading:18926644-Cote d'Ivoire,
pubmed-meshheading:18926644-Cross Infection,
pubmed-meshheading:18926644-DNA, Bacterial,
pubmed-meshheading:18926644-Drug Resistance, Multiple, Bacterial,
pubmed-meshheading:18926644-Enterobacteriaceae,
pubmed-meshheading:18926644-Enterobacteriaceae Infections,
pubmed-meshheading:18926644-Genes, Bacterial,
pubmed-meshheading:18926644-Humans,
pubmed-meshheading:18926644-Polymerase Chain Reaction,
pubmed-meshheading:18926644-Quinolones,
pubmed-meshheading:18926644-Species Specificity,
pubmed-meshheading:18926644-Substrate Specificity,
pubmed-meshheading:18926644-beta-Lactam Resistance,
pubmed-meshheading:18926644-beta-Lactamases
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| pubmed:articleTitle |
[Qnr-type quinolone resistance in extended-spectrum beta-lactamase producing enterobacteria in Abidjan, Ivory Coast].
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| pubmed:affiliation |
Laboratoire de bactériologie-virologie, institut Pasteur, BP 1563, Abidjan 08, Côte d'Ivoire. guessennd@yahoo.fr
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| pubmed:publicationType |
Journal Article,
English Abstract,
Research Support, Non-U.S. Gov't
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