Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
7
|
| pubmed:dateCreated |
1991-10-15
|
| pubmed:abstractText |
The incidence of late-onset bleb-related endophthalmitis was evaluated retrospectively in 229 consecutive trabeculectomies performed with adjunctive 5-fluorouracil (5-FU) therapy. Mean follow-up was 23.7 +/- 16.3 months (range, 3 to 60 months). Thirteen eyes (5.7%) of 11 patients developed bleb-related endophthalmitis an average of 25.9 +/- 17.4 months (range, 5 to 58 months) after surgery. Infection occurred in 9 of 96 (9.4%) procedures performed from below and in 4 of 133 (3.0%) procedures performed superiorly (P = 0.05, Fisher's exact test). The relative risk of bleb-related endophthalmitis in trabeculectomy from below versus above is 4.0 after adjustment for age and sex (95% confidence interval = 1.1, 14.8). Trabeculectomy with adjunctive 5-FU performed from below carries an increased risk of late bleb-related infection. The incidence of late bleb-related endophthalmitis after 5-FU trabeculectomy appears to be higher than that for trabeculectomy without adjunctive 5-FU injections.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jul
|
| pubmed:issn |
0161-6420
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
98
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1053-60
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:1891213-Adolescent,
pubmed-meshheading:1891213-Adult,
pubmed-meshheading:1891213-Aged,
pubmed-meshheading:1891213-Aged, 80 and over,
pubmed-meshheading:1891213-Anti-Bacterial Agents,
pubmed-meshheading:1891213-Child,
pubmed-meshheading:1891213-Child, Preschool,
pubmed-meshheading:1891213-Endophthalmitis,
pubmed-meshheading:1891213-Eye Infections, Bacterial,
pubmed-meshheading:1891213-Female,
pubmed-meshheading:1891213-Fluorouracil,
pubmed-meshheading:1891213-Follow-Up Studies,
pubmed-meshheading:1891213-Glaucoma,
pubmed-meshheading:1891213-Humans,
pubmed-meshheading:1891213-Incidence,
pubmed-meshheading:1891213-Intraocular Pressure,
pubmed-meshheading:1891213-Male,
pubmed-meshheading:1891213-Middle Aged,
pubmed-meshheading:1891213-Retrospective Studies,
pubmed-meshheading:1891213-Risk Factors,
pubmed-meshheading:1891213-Trabeculectomy,
pubmed-meshheading:1891213-Visual Acuity
|
| pubmed:year |
1991
|
| pubmed:articleTitle |
Late bleb-related endophthalmitis after trabeculectomy with adjunctive 5-fluorouracil.
|
| pubmed:affiliation |
Department of Ophthalmology, New York Eye and Ear Infirmary, New York City 10003.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|