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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:dateCreated |
1991-10-15
|
| pubmed:abstractText |
Fourty successive adult patients with lymphoblastic lymphoma entered a study of sequential chemotherapy consisting of an intensive LSA-L2-type protocol to induce first complete remission. Twenty-one patients in first CR (median age 24 years, range 15-43), after receiving a conditioning regimen consisting of cyclophosphamide and total body irradiation, underwent autologous bone marrow transplantation. At this time fourteen patients are alive and well 5-72 months post-transplant (median follow-up 58 months) with an actuarial disease free survival of 66%. These early results suggest that high-dose chemoradiotherapy followed by autologous bone marrow transplantation may improve long-term disease free survival in advanced stage adult lymphoblastic lymphoma.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0887-6924
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
5 Suppl 1
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
N
|
| pubmed:pagination |
42-5
|
| pubmed:dateRevised |
2007-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:1890865-Adult,
pubmed-meshheading:1890865-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:1890865-Bone Marrow Transplantation,
pubmed-meshheading:1890865-Female,
pubmed-meshheading:1890865-Humans,
pubmed-meshheading:1890865-Male,
pubmed-meshheading:1890865-Precursor Cell Lymphoblastic Leukemia-Lymphoma,
pubmed-meshheading:1890865-Prospective Studies,
pubmed-meshheading:1890865-Survival Analysis
|
| pubmed:year |
1991
|
| pubmed:articleTitle |
Autologous bone marrow transplantation for adult advanced stage lymphoblastic lymphoma in first CR. A study of the NHLCSG.
|
| pubmed:affiliation |
Division of Hematology, Ospedale S. Martino, Genoa, Italy.
|
| pubmed:publicationType |
Journal Article
|