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rdf:type |
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lifeskim:mentions |
umls-concept:C0010592,
umls-concept:C0022646,
umls-concept:C0022671,
umls-concept:C0030705,
umls-concept:C0035647,
umls-concept:C0085149,
umls-concept:C0175668,
umls-concept:C0205191,
umls-concept:C0231174,
umls-concept:C0450127,
umls-concept:C1948041,
umls-concept:C2603343
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pubmed:issue |
7
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pubmed:dateCreated |
2008-10-14
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|
pubmed:abstractText |
Chronic allograft nephropathy is the most frequent cause of long-term kidney allograft loss. Studies are desperately needed to improve long-term survival. Tacrolimus has been associated with less rejection and better kidney function compared with cyclosporine in clinical trials. This study tested the hypothesis that conversion from cyclosporine to tacrolimus might improve long-term outcomes in patients with chronic allograft damage.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1534-6080
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pubmed:author |
pubmed-author:ArlenDianneD,
pubmed-author:BarrettBrendanB,
pubmed-author:BoucherAnneA,
pubmed-author:CardellaCarlC,
pubmed-author:CockfieldSandra MSM,
pubmed-author:JevnikarAnthonyA,
pubmed-author:KiberdBryceB,
pubmed-author:ParaskevasStevenS,
pubmed-author:RushDavidD,
pubmed-author:ShapiroJeanJ,
pubmed-author:ShokerAhmedA,
pubmed-author:YilmazSerdarS,
pubmed-author:ZaltzmanJeffrey SJS
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pubmed:issnType |
Electronic
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pubmed:day |
15
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pubmed:volume |
86
|
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
953-60
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pubmed:meshHeading |
pubmed-meshheading:18852662-Adult,
pubmed-meshheading:18852662-Cadaver,
pubmed-meshheading:18852662-Cyclosporine,
pubmed-meshheading:18852662-Follow-Up Studies,
pubmed-meshheading:18852662-Glomerular Filtration Rate,
pubmed-meshheading:18852662-Graft Rejection,
pubmed-meshheading:18852662-Humans,
pubmed-meshheading:18852662-Immunosuppressive Agents,
pubmed-meshheading:18852662-Kidney Transplantation,
pubmed-meshheading:18852662-Living Donors,
pubmed-meshheading:18852662-Middle Aged,
pubmed-meshheading:18852662-Survival Analysis,
pubmed-meshheading:18852662-Survivors,
pubmed-meshheading:18852662-Tacrolimus,
pubmed-meshheading:18852662-Telephone,
pubmed-meshheading:18852662-Time Factors,
pubmed-meshheading:18852662-Tissue Donors,
pubmed-meshheading:18852662-Treatment Failure,
pubmed-meshheading:18852662-Treatment Outcome
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pubmed:year |
2008
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pubmed:articleTitle |
Five-year study of tacrolimus as secondary intervention versus continuation of cyclosporine in renal transplant patients at risk for chronic renal allograft failure.
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pubmed:affiliation |
London Health Sciences Centre, University Campus, London, ON, Canada.
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
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