Source:http://linkedlifedata.com/resource/pubmed/id/18851858
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
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| pubmed:dateCreated |
2009-2-16
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| pubmed:abstractText |
Electroconvulsive therapy (ECT) is one of the most effective options available for treating depressive and psychotic symptoms in a variety of disorders. While the exact mechanism of ECT is unclear, it is known to increase metabolism and blood flow specifically in the anterior cingulate cortex (ACC). The ACC is a cortical generator of theta rhythms, which are abnormal in patients with depression and psychotic disorders. Since patients with psychotic depression are known to respond particularly robustly to ECT, we investigated whether the therapeutic effect of ECT in this population was related to normalization of abnormal theta activity in the ACC.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:status |
MEDLINE
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| pubmed:month |
Feb
|
| pubmed:issn |
0022-3956
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| pubmed:author | |
| pubmed:issnType |
Print
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| pubmed:volume |
43
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
553-60
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| pubmed:meshHeading |
pubmed-meshheading:18851858-Adult,
pubmed-meshheading:18851858-Brain Mapping,
pubmed-meshheading:18851858-Cognition,
pubmed-meshheading:18851858-Depressive Disorder,
pubmed-meshheading:18851858-Electroconvulsive Therapy,
pubmed-meshheading:18851858-Electroencephalography,
pubmed-meshheading:18851858-Female,
pubmed-meshheading:18851858-Follow-Up Studies,
pubmed-meshheading:18851858-Gyrus Cinguli,
pubmed-meshheading:18851858-Humans,
pubmed-meshheading:18851858-Image Processing, Computer-Assisted,
pubmed-meshheading:18851858-Imaging, Three-Dimensional,
pubmed-meshheading:18851858-Male,
pubmed-meshheading:18851858-Memory,
pubmed-meshheading:18851858-Middle Aged,
pubmed-meshheading:18851858-Psychotic Disorders,
pubmed-meshheading:18851858-Theta Rhythm,
pubmed-meshheading:18851858-Tomography, X-Ray Computed,
pubmed-meshheading:18851858-Treatment Outcome,
pubmed-meshheading:18851858-Young Adult
|
| pubmed:year |
2009
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| pubmed:articleTitle |
Antipsychotic effect of electroconvulsive therapy is related to normalization of subgenual cingulate theta activity in psychotic depression.
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| pubmed:affiliation |
Department of Psychiatry, University of Iowa, Carver College of Medicine, Psychiatric Iowa Neuroimaging Center, 200 Hawkins Drive, W278 GH, Iowa City, IA 52242, USA. laurie-mccormick@uiowa.edu
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| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|