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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2008-11-27
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pubmed:abstractText |
Mitochondrial DNA (mtDNA) mutations, inherited and somatically acquired, are common in clinical prostate cancer. We have developed model systems designed to study specific mtDNA mutations in controlled experiments. Because prostate cancer frequently metastasizes to bone we tested the hypothesis that mtDNA mutations enhance prostate cancer growth and survival in the bone microenvironment.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/18850577-10409242,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18850577-10629559,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18850577-11327323,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18850577-11356940,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18850577-11526508,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18850577-11922392,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18850577-12094550,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18850577-12185249,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18850577-12242727,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18850577-12438238,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18850577-14555628,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18850577-15647368,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18850577-16039164,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18850577-16510472,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18850577-16825503,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18850577-16892079,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18850577-17879999,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18850577-18388260,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18850577-7693336,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18850577-8078883,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18850577-8476414,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18850577-8834172,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18850577-8843417,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18850577-8900422,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18850577-9072001,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18850577-9806551
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1097-0045
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pubmed:author |
pubmed-author:ArnoldRebecca SRS,
pubmed-author:ChungLelandL,
pubmed-author:ColemanIlsa MIM,
pubmed-author:GrigorievGalinaG,
pubmed-author:HsiehChia-LingCL,
pubmed-author:LeeJae KJK,
pubmed-author:NelsonPeter SPS,
pubmed-author:OsunkoyaAdeboye OAO,
pubmed-author:PetrosJohn AJA,
pubmed-author:RichardsJendai CJC,
pubmed-author:RogatkoAndreA,
pubmed-author:SunCarrie QCQ,
pubmed-author:XuZhihengZ,
pubmed-author:ZayzafoonMajdM
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pubmed:copyrightInfo |
Copyright 2008 Wiley-Liss, Inc
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pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
69
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1-11
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pubmed:dateRevised |
2011-5-5
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pubmed:meshHeading |
pubmed-meshheading:18850577-Animals,
pubmed-meshheading:18850577-Bone Neoplasms,
pubmed-meshheading:18850577-Bone and Bones,
pubmed-meshheading:18850577-Cell Division,
pubmed-meshheading:18850577-Cell Line, Tumor,
pubmed-meshheading:18850577-Cell Movement,
pubmed-meshheading:18850577-Cell Survival,
pubmed-meshheading:18850577-DNA, Mitochondrial,
pubmed-meshheading:18850577-Disease Models, Animal,
pubmed-meshheading:18850577-Fibroblast Growth Factor 1,
pubmed-meshheading:18850577-Focal Adhesion Protein-Tyrosine Kinases,
pubmed-meshheading:18850577-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:18850577-Humans,
pubmed-meshheading:18850577-Male,
pubmed-meshheading:18850577-Mice,
pubmed-meshheading:18850577-Mice, Nude,
pubmed-meshheading:18850577-Mutation,
pubmed-meshheading:18850577-Neoplasm Transplantation,
pubmed-meshheading:18850577-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:18850577-Prostatic Neoplasms,
pubmed-meshheading:18850577-Stromal Cells,
pubmed-meshheading:18850577-Transplantation, Heterologous
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pubmed:year |
2009
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pubmed:articleTitle |
Mitochondrial DNA mutation stimulates prostate cancer growth in bone stromal environment.
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pubmed:affiliation |
Department of Urology, Emory University School of Medicine, Atlanta, Georgia 30322, USA.
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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