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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2008-11-18
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pubmed:abstractText |
Recent studies demonstrated that the Period1 gene (Per1) is involved in behavioral alterations induced by addictive drugs. We explored the effects of inhibiting expression in brain of Per1 on morphine conditioned place preference (CPP) and morphine-induced phosphorylation of extracellular signal-regulated kinase (ERK) and cAMP-response element binding protein (CREB) in mice.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Cell Cycle Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclic AMP Response...,
http://linkedlifedata.com/resource/pubmed/chemical/DNA, Catalytic,
http://linkedlifedata.com/resource/pubmed/chemical/Extracellular Signal-Regulated MAP...,
http://linkedlifedata.com/resource/pubmed/chemical/Morphine,
http://linkedlifedata.com/resource/pubmed/chemical/Nuclear Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Per1 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Period Circadian Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger
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pubmed:status |
MEDLINE
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pubmed:issn |
1097-9891
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
34
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
673-82
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:18850497-Animals,
pubmed-meshheading:18850497-Cell Cycle Proteins,
pubmed-meshheading:18850497-Conditioning, Operant,
pubmed-meshheading:18850497-Corpus Striatum,
pubmed-meshheading:18850497-Cyclic AMP Response Element-Binding Protein,
pubmed-meshheading:18850497-DNA, Catalytic,
pubmed-meshheading:18850497-Drug Delivery Systems,
pubmed-meshheading:18850497-Extracellular Signal-Regulated MAP Kinases,
pubmed-meshheading:18850497-Frontal Lobe,
pubmed-meshheading:18850497-Gene Expression Regulation,
pubmed-meshheading:18850497-Hippocampus,
pubmed-meshheading:18850497-Male,
pubmed-meshheading:18850497-Mice,
pubmed-meshheading:18850497-Mice, Inbred BALB C,
pubmed-meshheading:18850497-Morphine,
pubmed-meshheading:18850497-Morphine Dependence,
pubmed-meshheading:18850497-Nuclear Proteins,
pubmed-meshheading:18850497-Period Circadian Proteins,
pubmed-meshheading:18850497-Phosphorylation,
pubmed-meshheading:18850497-RNA, Messenger,
pubmed-meshheading:18850497-Reward
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pubmed:year |
2008
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pubmed:articleTitle |
Inhibition of Period1 gene attenuates the morphine-induced ERK-CREB activation in frontal cortex, hippocampus, and striatum in mice.
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pubmed:affiliation |
Key Laboratory of Chronobiology of Health Ministry, Basic and Forensic School, Sichuan University, Chengdu, China. lisuxia70@163.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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