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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2008-11-25
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pubmed:abstractText |
Loss to follow-up is a major source of bias in cohorts of patients with human immunodeficiency virus (HIV) and could lead to underestimation of mortality. The authors developed a hierarchical deterministic linkage algorithm to be used primarily with cohorts of HIV-infected persons to recover vital status information for patients lost to follow-up. Data from patients known to be deceased in 2 cohorts in Rio de Janeiro, Brazil, and data from the Rio de Janeiro State mortality database for 1999-2006 were used to validate the algorithm. A fully automated procedure yielded a sensitivity of 92.9% and specificity of 100% when no information was missing. When the automated procedure was combined with clerical review, in a scenario of 5% death prevalence and 20% missing mothers' names, sensitivity reached 96.5% and specificity 100%. In a practical application, the algorithm significantly increased death rates and decreased the rate of loss to follow-up in the cohorts. The finding that 23.9% of matched records did not give HIV or acquired immunodeficiency syndrome as the cause of death reinforces the need to search all-cause mortality databases and alerts for possible underestimation of death rates. These results indicate that the algorithm is accurate enough to recover vital status information on patients lost to follow-up in cohort studies.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/18849301-10883042,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18849301-11085393,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18849301-11277828,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18849301-12185898,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18849301-14426783,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18849301-15076249,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18849301-15178677,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18849301-15742989,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18849301-16530575,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18849301-16597337,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18849301-16951897,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18849301-17311840,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18849301-17456522,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18849301-17589190,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18849301-18097233,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18849301-7905525,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18849301-8543958,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18849301-8563310,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18849301-8656723,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18849301-9421866,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18849301-9762514
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1476-6256
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pubmed:author |
pubmed-author:CavalcanteSolange CSC,
pubmed-author:ChaissonRichard ERE,
pubmed-author:DurovniBetinaB,
pubmed-author:FaulhaberJosé CJC,
pubmed-author:GolubJonathan EJE,
pubmed-author:HarrisonLee HLH,
pubmed-author:KingBonnieB,
pubmed-author:MoultonLawrence HLH,
pubmed-author:PachecoAntonio GAG,
pubmed-author:SaraceniValeriaV,
pubmed-author:SchechterMauroM,
pubmed-author:TuboiSuely HSH
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pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
168
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1326-32
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pubmed:dateRevised |
2011-1-20
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pubmed:meshHeading |
pubmed-meshheading:18849301-Adolescent,
pubmed-meshheading:18849301-Adult,
pubmed-meshheading:18849301-Algorithms,
pubmed-meshheading:18849301-Brazil,
pubmed-meshheading:18849301-Cohort Studies,
pubmed-meshheading:18849301-Databases, Factual,
pubmed-meshheading:18849301-Death Certificates,
pubmed-meshheading:18849301-Female,
pubmed-meshheading:18849301-HIV Infections,
pubmed-meshheading:18849301-Humans,
pubmed-meshheading:18849301-Male,
pubmed-meshheading:18849301-Medical Record Linkage,
pubmed-meshheading:18849301-Sensitivity and Specificity,
pubmed-meshheading:18849301-Survival Rate,
pubmed-meshheading:18849301-Tuberculosis, Pulmonary
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pubmed:year |
2008
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pubmed:articleTitle |
Validation of a hierarchical deterministic record-linkage algorithm using data from 2 different cohorts of human immunodeficiency virus-infected persons and mortality databases in Brazil.
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pubmed:affiliation |
Programa de Computação Científica, Fundação Oswaldo Cruz, Avenida Brasil 4365, Manguinhos, 21045-360 Rio de Janeiro, Brazil. apacheco@fiocruz.br
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural,
Validation Studies
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