Source:http://linkedlifedata.com/resource/pubmed/id/18848731
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2008-10-28
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pubmed:abstractText |
This report describes the measurement properties of the Personal and Social Performance scale (PSP), a clinician-reported measure of severity of personal and social dysfunction, in an outpatient population with stabilized schizophrenia. Pooled data from two similar antipsychotic clinical studies were analyzed (n=411). The PSP showed good test-retest reliability (intraclass correlation coefficient=0.79). The PSP was more highly correlated with the Strauss-Carpenter Level of Function, an instrument measuring a similar construct, than the Positive and Negative Syndrome Scale, an instrument measuring a different construct. There was a statistically significant difference between mean PSP scores in subjects grouped by their severity rating on the Clinical Global Impression-Severity (CGI-S) (mild or less versus at least moderate), indicating the ability to discriminate between known groups. Effect sizes for mean change in the PSP based on 1-category improvement (0.72) or worsening (-0.88) versus no change in the CGI-S were moderate to large, demonstrating the ability to detect change. Estimates of between-group minimum important difference suggest that a 7-point improvement in the PSP may be clinically meaningful in a clinical trial setting. Initial reliability and validity assessments suggest the PSP may be a useful measure of social functioning in patients with stable schizophrenia.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0165-1781
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
30
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pubmed:volume |
161
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
213-24
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pubmed:meshHeading |
pubmed-meshheading:18848731-Adult,
pubmed-meshheading:18848731-Ambulatory Care,
pubmed-meshheading:18848731-Antipsychotic Agents,
pubmed-meshheading:18848731-Diagnostic and Statistical Manual of Mental Disorders,
pubmed-meshheading:18848731-Female,
pubmed-meshheading:18848731-Humans,
pubmed-meshheading:18848731-Male,
pubmed-meshheading:18848731-Outcome Assessment (Health Care),
pubmed-meshheading:18848731-Psychiatric Status Rating Scales,
pubmed-meshheading:18848731-Psychometrics,
pubmed-meshheading:18848731-Quality of Life,
pubmed-meshheading:18848731-Questionnaires,
pubmed-meshheading:18848731-Reproducibility of Results,
pubmed-meshheading:18848731-Risperidone,
pubmed-meshheading:18848731-Schizophrenia,
pubmed-meshheading:18848731-Schizophrenic Psychology,
pubmed-meshheading:18848731-Social Adjustment
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pubmed:year |
2008
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pubmed:articleTitle |
Reliability, validity and ability to detect change of the Personal and Social Performance scale in patients with stable schizophrenia.
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pubmed:affiliation |
University of Cincinnati, Department of Psychiatry, Cincinnati, OH 45267-0559, USA. henry.nasrallah@uc.edu
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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