Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2008-10-28
pubmed:abstractText
This report describes the measurement properties of the Personal and Social Performance scale (PSP), a clinician-reported measure of severity of personal and social dysfunction, in an outpatient population with stabilized schizophrenia. Pooled data from two similar antipsychotic clinical studies were analyzed (n=411). The PSP showed good test-retest reliability (intraclass correlation coefficient=0.79). The PSP was more highly correlated with the Strauss-Carpenter Level of Function, an instrument measuring a similar construct, than the Positive and Negative Syndrome Scale, an instrument measuring a different construct. There was a statistically significant difference between mean PSP scores in subjects grouped by their severity rating on the Clinical Global Impression-Severity (CGI-S) (mild or less versus at least moderate), indicating the ability to discriminate between known groups. Effect sizes for mean change in the PSP based on 1-category improvement (0.72) or worsening (-0.88) versus no change in the CGI-S were moderate to large, demonstrating the ability to detect change. Estimates of between-group minimum important difference suggest that a 7-point improvement in the PSP may be clinically meaningful in a clinical trial setting. Initial reliability and validity assessments suggest the PSP may be a useful measure of social functioning in patients with stable schizophrenia.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0165-1781
pubmed:author
pubmed:issnType
Print
pubmed:day
30
pubmed:volume
161
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
213-24
pubmed:meshHeading
pubmed-meshheading:18848731-Adult, pubmed-meshheading:18848731-Ambulatory Care, pubmed-meshheading:18848731-Antipsychotic Agents, pubmed-meshheading:18848731-Diagnostic and Statistical Manual of Mental Disorders, pubmed-meshheading:18848731-Female, pubmed-meshheading:18848731-Humans, pubmed-meshheading:18848731-Male, pubmed-meshheading:18848731-Outcome Assessment (Health Care), pubmed-meshheading:18848731-Psychiatric Status Rating Scales, pubmed-meshheading:18848731-Psychometrics, pubmed-meshheading:18848731-Quality of Life, pubmed-meshheading:18848731-Questionnaires, pubmed-meshheading:18848731-Reproducibility of Results, pubmed-meshheading:18848731-Risperidone, pubmed-meshheading:18848731-Schizophrenia, pubmed-meshheading:18848731-Schizophrenic Psychology, pubmed-meshheading:18848731-Social Adjustment
pubmed:year
2008
pubmed:articleTitle
Reliability, validity and ability to detect change of the Personal and Social Performance scale in patients with stable schizophrenia.
pubmed:affiliation
University of Cincinnati, Department of Psychiatry, Cincinnati, OH 45267-0559, USA. henry.nasrallah@uc.edu
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't