Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2008-10-13
pubmed:abstractText
The bisphosphonates (BP) are well established as the treatment of choice for disorders of excessive bone resorption. Their classical pharmacological effects appear to result from two key properties: affinity for bone mineral and inhibitory effects on osteoclasts. Presented paper contains overview of the most important information concerning application of bisphosphonates in orthopedics. This compilation has been extended and includes also cellular mechanisms of action, pharmacological classification as well as adverse effects of this drugs' group. The most significant differences between the various individual BP and basic pharmacokinetic properties have been shown. This manuscript presents clinical guidelines on safe bisphosphonates usage.
pubmed:language
pol
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0009-479X
pubmed:author
pubmed:issnType
Print
pubmed:volume
73
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
266-73
pubmed:meshHeading
pubmed:articleTitle
[The use of bisphosphonates for treating pathological states in orthopedics].
pubmed:affiliation
Katedra i Klinika Ortopedii i Traumatologii, Pomorska Akademia Medyczna w Szczecinie.
pubmed:publicationType
Journal Article, English Abstract, Review