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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2008-10-10
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pubmed:abstractText |
Surveillance of hepatocellular carcinoma (HCC) can detect small tumors for resection but at a huge cost of health resources. The challenge is to reduce the surveillance population. We reported that 96% of HCC patients but only 24% of controls were infected with the hepatitis B virus (HBV) with A(1762)T, G(1764)A mutations in Guangxi, China. It is likely to be extremely beneficial in terms of cost and resources if a significant number of tumors can be detected early by screening this selected population. Our aim is to test this hypothesis.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/18844615-10051502,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18844615-10533799,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18844615-10655254,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18844615-11685737,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18844615-12100608,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18844615-12124470,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18844615-12210428,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18844615-12500184,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18844615-12516404,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18844615-12557138,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18844615-14990795,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18844615-15042359,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18844615-15151623,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18844615-15361502,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18844615-15713961,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18844615-15757802,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18844615-15818732,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18844615-15910494,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18844615-16333089,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18844615-16618410,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18844615-16897657,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18844615-16935384,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18844615-17376881,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18844615-17451999,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18844615-17483190,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/18844615-2539905,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18844615-3171552,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18844615-6118576,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/18844615-9700628,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18844615-9752506
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1572-0241
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
103
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2254-62
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:18844615-Adult,
pubmed-meshheading:18844615-Carcinoma, Hepatocellular,
pubmed-meshheading:18844615-Chi-Square Distribution,
pubmed-meshheading:18844615-China,
pubmed-meshheading:18844615-Hepatitis B Surface Antigens,
pubmed-meshheading:18844615-Hepatitis B virus,
pubmed-meshheading:18844615-Humans,
pubmed-meshheading:18844615-Liver Neoplasms,
pubmed-meshheading:18844615-Male,
pubmed-meshheading:18844615-Middle Aged,
pubmed-meshheading:18844615-Mutation,
pubmed-meshheading:18844615-Poisson Distribution,
pubmed-meshheading:18844615-Polymerase Chain Reaction,
pubmed-meshheading:18844615-Prospective Studies,
pubmed-meshheading:18844615-Risk Factors,
pubmed-meshheading:18844615-Rural Population,
pubmed-meshheading:18844615-Tumor Markers, Biological
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pubmed:year |
2008
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pubmed:articleTitle |
HBV A1762T, G1764A mutations are a valuable biomarker for identifying a subset of male HBsAg carriers at extremely high risk of hepatocellular carcinoma: a prospective study.
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pubmed:affiliation |
Department of Medicine, Royal Free and University College Medical School, University College London, London, United Kingdom.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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