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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
Pt 10
pubmed:dateCreated
2008-10-9
pubmed:databankReference
pubmed:abstractText
A yellow-pigmented, scotochromogenic, slowly growing mycobacterial strain, designated T1921(T), was isolated from the disseminated osteomyelitic lesions of a 7-year-old child with an underlying partial gamma interferon receptor alpha-1 deficiency. Hybridization by the line probe assay indicated the presence of a Mycobacterium species. Sequencing of the 16S rRNA gene, the internally transcribed spacer (ITS) region and the hsp65 and rpoB genes revealed that strain T1921(T) could be differentiated from all recognized species of the genus Mycobacterium. Phylogenetic analysis based on the 16S rRNA gene indicated that strain T1921(T) was related most closely to Mycobacterium intracellulare, whereas analysis based on the ITS and hsp65 and rpoB genes indicated that it was most closely related to Mycobacterium avium. Phenotypic tests were not able to differentiate strain T1921(T) from similar slowly growing mycobacteria. Strain T1921(T) is considered to represent a novel species of the genus Mycobacterium, for which the name Mycobacterium arosiense sp. nov. is proposed. The type strain is T1921(T) (=DSM 45069(T) =ATCC BAA-1401(T)).
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1466-5026
pubmed:author
pubmed:issnType
Print
pubmed:volume
58
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2398-402
pubmed:meshHeading
pubmed-meshheading:18842863-Bacterial Typing Techniques, pubmed-meshheading:18842863-Child, pubmed-meshheading:18842863-DNA, Bacterial, pubmed-meshheading:18842863-DNA, Ribosomal Spacer, pubmed-meshheading:18842863-Fatty Acids, pubmed-meshheading:18842863-Female, pubmed-meshheading:18842863-Genes, Bacterial, pubmed-meshheading:18842863-Genes, rRNA, pubmed-meshheading:18842863-Humans, pubmed-meshheading:18842863-Immunocompromised Host, pubmed-meshheading:18842863-Microbial Sensitivity Tests, pubmed-meshheading:18842863-Molecular Sequence Data, pubmed-meshheading:18842863-Mycobacterium, pubmed-meshheading:18842863-Mycobacterium Infections, pubmed-meshheading:18842863-Osteomyelitis, pubmed-meshheading:18842863-Phylogeny, pubmed-meshheading:18842863-RNA, Ribosomal, 16S, pubmed-meshheading:18842863-Sequence Analysis, DNA
pubmed:year
2008
pubmed:articleTitle
Mycobacterium arosiense sp. nov., a slowly growing, scotochromogenic species causing osteomyelitis in an immunocompromised child.
pubmed:affiliation
International Reference Laboratory of Mycobacteriology and National Center for Antimicrobials and Infection Control, Statens Serum Institut, Artillerivej 5, DK-2300 Copenhagen, Denmark. DVB@ssi.dk
pubmed:publicationType
Journal Article