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rdf:type |
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lifeskim:mentions |
umls-concept:C0006644,
umls-concept:C0008059,
umls-concept:C0011816,
umls-concept:C0023981,
umls-concept:C0205127,
umls-concept:C0271561,
umls-concept:C0384570,
umls-concept:C0559956,
umls-concept:C1285572,
umls-concept:C1314763,
umls-concept:C2603343
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pubmed:issue |
9
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pubmed:dateCreated |
2008-10-8
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pubmed:abstractText |
Recombinant human growth hormone (r-hGH) is increasingly being used in children. Although growth hormone (GH) may alter the clearance of concomitantly administered medications, its effects on individual drug-metabolizing enzymes in children have not been characterized.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Arylamine N-Acetyltransferase,
http://linkedlifedata.com/resource/pubmed/chemical/Caffeine,
http://linkedlifedata.com/resource/pubmed/chemical/Central Nervous System Stimulants,
http://linkedlifedata.com/resource/pubmed/chemical/Cytochrome P-450 CYP1A2,
http://linkedlifedata.com/resource/pubmed/chemical/Cytochrome P-450 CYP2D6,
http://linkedlifedata.com/resource/pubmed/chemical/Dextromethorphan,
http://linkedlifedata.com/resource/pubmed/chemical/Human Growth Hormone,
http://linkedlifedata.com/resource/pubmed/chemical/Insulin-Like Growth Factor I,
http://linkedlifedata.com/resource/pubmed/chemical/NAT2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Recombinant Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Xanthine Oxidase
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0149-2918
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
30
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1687-99
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pubmed:dateRevised |
2010-9-8
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pubmed:meshHeading |
pubmed-meshheading:18840375-Adolescent,
pubmed-meshheading:18840375-Arylamine N-Acetyltransferase,
pubmed-meshheading:18840375-Caffeine,
pubmed-meshheading:18840375-Central Nervous System Stimulants,
pubmed-meshheading:18840375-Child,
pubmed-meshheading:18840375-Child, Preschool,
pubmed-meshheading:18840375-Cytochrome P-450 CYP1A2,
pubmed-meshheading:18840375-Cytochrome P-450 CYP2D6,
pubmed-meshheading:18840375-Dextromethorphan,
pubmed-meshheading:18840375-Dwarfism, Pituitary,
pubmed-meshheading:18840375-Female,
pubmed-meshheading:18840375-Growth Disorders,
pubmed-meshheading:18840375-Human Growth Hormone,
pubmed-meshheading:18840375-Humans,
pubmed-meshheading:18840375-Insulin-Like Growth Factor I,
pubmed-meshheading:18840375-Longitudinal Studies,
pubmed-meshheading:18840375-Male,
pubmed-meshheading:18840375-Phenotype,
pubmed-meshheading:18840375-Prospective Studies,
pubmed-meshheading:18840375-Recombinant Proteins,
pubmed-meshheading:18840375-Xanthine Oxidase
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pubmed:year |
2008
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pubmed:articleTitle |
Six-month, prospective, longitudinal, open-label caffeine and dextromethorphan phenotyping study in children with growth hormone deficiency receiving recombinant human growth hormone replacement.
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pubmed:affiliation |
Kosair Charities Pediatric Clinical Research Unit, Department of Pediatrics, School of Medicine, University of Louisville, Louisville, Kentucky 40202, USA. mjkenn07@louisville.edu
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Multicenter Study,
Research Support, N.I.H., Extramural
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