Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2009-2-9
pubmed:abstractText
We use direct femtosecond laser writing to integrate optical waveguides into a commercial fused silica capillary electrophoresis chip. High-quality waveguides crossing the microfluidic channels are fabricated and used to optically address, with high spatial selectivity, their content. Fluorescence from the optically excited volume is efficiently collected at a 90 degree angle by a high numerical aperture fiber, resulting in a highly compact and portable device. To test the platform we performed electrophoresis and detection of a 23-mer oligonucleotide plug. Our approach is quite powerful because it allows the integration of photonic functionalities, by simple post-processing, into commercial LOCs fabricated with standard techniques.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1618-2650
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
393
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1209-16
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Optical sensing in microfluidic lab-on-a-chip by femtosecond-laser-written waveguides.
pubmed:affiliation
Istituto di Fotonica e Nanotecnologie-CNR, Dipartimento di Fisica, Politecnico di Milano, Piazza Leonardo da Vinci, 32, 20133, Milan, Italy.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't