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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2008-10-7
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pubmed:abstractText |
The benzodiazepine (BZD) receptor system has been implicated in the pathophysiologic mechanism of panic disorder (PD) by indirect evidence from pharmacological challenge studies and by direct evidence from single-photon emission computed tomography and positron emission tomography neuroimaging studies. However, the results of previous neuroimaging studies are in disagreement, possibly because of experimental design limitations related to sample size, matching between patients and controls, and confounding medication effects.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1538-3636
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
65
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1166-75
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pubmed:meshHeading |
pubmed-meshheading:18838633-Adult,
pubmed-meshheading:18838633-Brain,
pubmed-meshheading:18838633-Brain Mapping,
pubmed-meshheading:18838633-Carbon Radioisotopes,
pubmed-meshheading:18838633-Cerebral Cortex,
pubmed-meshheading:18838633-Comorbidity,
pubmed-meshheading:18838633-Depressive Disorder, Major,
pubmed-meshheading:18838633-Dominance, Cerebral,
pubmed-meshheading:18838633-Female,
pubmed-meshheading:18838633-Flumazenil,
pubmed-meshheading:18838633-Gyrus Cinguli,
pubmed-meshheading:18838633-Hippocampus,
pubmed-meshheading:18838633-Humans,
pubmed-meshheading:18838633-Image Processing, Computer-Assisted,
pubmed-meshheading:18838633-Magnetic Resonance Imaging,
pubmed-meshheading:18838633-Male,
pubmed-meshheading:18838633-Middle Aged,
pubmed-meshheading:18838633-Panic Disorder,
pubmed-meshheading:18838633-Parahippocampal Gyrus,
pubmed-meshheading:18838633-Positron-Emission Tomography,
pubmed-meshheading:18838633-Receptors, GABA-A,
pubmed-meshheading:18838633-Reference Values,
pubmed-meshheading:18838633-Software
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pubmed:year |
2008
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pubmed:articleTitle |
Altered cerebral gamma-aminobutyric acid type A-benzodiazepine receptor binding in panic disorder determined by [11C]flumazenil positron emission tomography.
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pubmed:affiliation |
Department of Psychiatry, University Hospital, Culmannstrasse 8, 8091 Zurich, Switzerland. g.hasler@bluewin.ch
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Intramural
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