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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2008-11-14
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pubmed:abstractText |
Previous studies have suggested that two subtypes of essential thrombocythemia (ET) could be separated on the basis of their JAK2 status (V617F-positive or V617F-negative), with a continuum between V617F-positive ET and polycythemia vera (PV). Nevertheless, increasingly contradictory data on the impact of JAK2-V617F (presence and load) on ET phenotype highlight the need for further investigations.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0301-472X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
36
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1642-7
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:18838204-Amino Acid Substitution,
pubmed-meshheading:18838204-Blood Proteins,
pubmed-meshheading:18838204-Female,
pubmed-meshheading:18838204-Genetic Diseases, Inborn,
pubmed-meshheading:18838204-Humans,
pubmed-meshheading:18838204-Janus Kinase 2,
pubmed-meshheading:18838204-Male,
pubmed-meshheading:18838204-Mutation, Missense,
pubmed-meshheading:18838204-Phenotype,
pubmed-meshheading:18838204-Polycythemia Vera,
pubmed-meshheading:18838204-Proteome,
pubmed-meshheading:18838204-Proteomics,
pubmed-meshheading:18838204-Thrombocythemia, Essential
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pubmed:year |
2008
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pubmed:articleTitle |
Proteomic study of the impact of the JAK2-V617F mutation on the phenotype of essential thrombocythemia.
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pubmed:affiliation |
Laboratoire d'hématologie cellulaire et moléculaire, DBPC, CHU Grenoble, France. PMossuz@chu-grenoble.fr
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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