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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2008-10-1
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pubmed:abstractText |
Epidermal growth factor receptor (EGFR) gene intron 1 contains a polymorphic single sequence dinucleotide repeat (CA)n whose length has been found to inversely correlate with transcriptional activity. This study was designed to assess the role of (CA)n polymorphism in predicting the outcome of gefitinib treatment in advanced non-small cell lung cancer (NSCLC).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1556-1380
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pubmed:author |
pubmed-author:AlfieriRoberta RRR,
pubmed-author:ArdizzoniAndreaA,
pubmed-author:BoniLucaL,
pubmed-author:BortesiBeatriceB,
pubmed-author:BozzettiCeciliaC,
pubmed-author:CamisaRobertaR,
pubmed-author:CapellettiMarziaM,
pubmed-author:CavazzoniAndreaA,
pubmed-author:De PalmaGiuseppeG,
pubmed-author:FranciosiVittorioV,
pubmed-author:GalettiMariclaM,
pubmed-author:GoldoniMatteoM,
pubmed-author:LopreviteMauraM,
pubmed-author:MozzoniPaolaP,
pubmed-author:PetroniniPier GiorgioPG,
pubmed-author:RindiGuidoG,
pubmed-author:TiseoMarcelloM
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pubmed:issnType |
Electronic
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pubmed:volume |
3
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1104-11
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:18827605-Adenocarcinoma,
pubmed-meshheading:18827605-Adult,
pubmed-meshheading:18827605-Aged,
pubmed-meshheading:18827605-Aged, 80 and over,
pubmed-meshheading:18827605-Carcinoma, Non-Small-Cell Lung,
pubmed-meshheading:18827605-Cell Proliferation,
pubmed-meshheading:18827605-DNA, Neoplasm,
pubmed-meshheading:18827605-Dinucleotide Repeats,
pubmed-meshheading:18827605-Female,
pubmed-meshheading:18827605-Gene Dosage,
pubmed-meshheading:18827605-Humans,
pubmed-meshheading:18827605-Immunoenzyme Techniques,
pubmed-meshheading:18827605-Introns,
pubmed-meshheading:18827605-Lung Neoplasms,
pubmed-meshheading:18827605-Male,
pubmed-meshheading:18827605-Middle Aged,
pubmed-meshheading:18827605-Neoplasm Staging,
pubmed-meshheading:18827605-Polymorphism, Genetic,
pubmed-meshheading:18827605-Prognosis,
pubmed-meshheading:18827605-Protein Kinase Inhibitors,
pubmed-meshheading:18827605-Quinazolines,
pubmed-meshheading:18827605-Receptor, Epidermal Growth Factor,
pubmed-meshheading:18827605-Survival Rate,
pubmed-meshheading:18827605-Treatment Outcome,
pubmed-meshheading:18827605-Tumor Markers, Biological
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pubmed:year |
2008
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pubmed:articleTitle |
Epidermal growth factor receptor intron-1 polymorphism predicts gefitinib outcome in advanced non-small cell lung cancer.
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pubmed:affiliation |
Division of Medical Oncology, University Hospital of Parma, Italy. mtiseo@ao.pr.it
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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