Source:http://linkedlifedata.com/resource/pubmed/id/18827459
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
2008-10-1
|
| pubmed:abstractText |
We investigated 2 Japanese siblings with a complicated form of familial spastic paraplegia. Cranial magnetic resonance (MR) imaging revealed marked thinning of the corpus callosum. Diffusion tensor imaging (DTI) showed microstructural changes in the thalamus, basal ganglia, and cerebral white matter, and single photon emission computed tomography (SPECT) using 99mTc-ethylcysteinate dimer showed very similar findings. DTI and SPECT effectively revealed global changes not revealed by conventional MR imaging.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
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| pubmed:issn |
1347-3182
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
7
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
163-7
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| pubmed:meshHeading |
pubmed-meshheading:18827459-Adolescent,
pubmed-meshheading:18827459-Adult,
pubmed-meshheading:18827459-Cognition Disorders,
pubmed-meshheading:18827459-Corpus Callosum,
pubmed-meshheading:18827459-Diffusion Magnetic Resonance Imaging,
pubmed-meshheading:18827459-Humans,
pubmed-meshheading:18827459-Male,
pubmed-meshheading:18827459-Paraplegia,
pubmed-meshheading:18827459-Reproducibility of Results,
pubmed-meshheading:18827459-Sensitivity and Specificity
|
| pubmed:year |
2008
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| pubmed:articleTitle |
Diffusion tensor imaging in familial spastic paraplegia with mental impairment and thin corpus callosum.
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| pubmed:affiliation |
Department of Radiology, National Center Hospital for Mental, Nervous and Muscular Disorders, National Center of Neurology and Psychiatry, Tokyo, Japan.
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| pubmed:publicationType |
Journal Article
|