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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2009-1-21
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pubmed:abstractText |
Renal hypoxia plays a role in the development of diabetic nephropathy, and may be mediated by overactivity of the renin-angiotensin-aldosterone system (RAAS). In this study the localization of cellular hypoxia in an experimental model of diabetic nephropathy was assessed, and the effect of the angiotensin-converting enzyme inhibitor perindopril on hypoxia evaluated.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1440-1797
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
13
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
721-9
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pubmed:meshHeading |
pubmed-meshheading:18826488-Angiotensin-Converting Enzyme Inhibitors,
pubmed-meshheading:18826488-Animals,
pubmed-meshheading:18826488-Anoxia,
pubmed-meshheading:18826488-Diabetes Mellitus, Experimental,
pubmed-meshheading:18826488-Diabetic Nephropathies,
pubmed-meshheading:18826488-Female,
pubmed-meshheading:18826488-Fibrosis,
pubmed-meshheading:18826488-Immunohistochemistry,
pubmed-meshheading:18826488-Inflammation,
pubmed-meshheading:18826488-Kidney Tubules,
pubmed-meshheading:18826488-Macrophages,
pubmed-meshheading:18826488-Nitroimidazoles,
pubmed-meshheading:18826488-Osteopontin,
pubmed-meshheading:18826488-Perindopril,
pubmed-meshheading:18826488-Rats,
pubmed-meshheading:18826488-Rats, Sprague-Dawley,
pubmed-meshheading:18826488-Rats, Transgenic,
pubmed-meshheading:18826488-Renin,
pubmed-meshheading:18826488-Renin-Angiotensin System,
pubmed-meshheading:18826488-Time Factors
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pubmed:year |
2008
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pubmed:articleTitle |
Perindopril attenuates tubular hypoxia and inflammation in an experimental model of diabetic nephropathy in transgenic Ren-2 rats.
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pubmed:affiliation |
Department of Medicine, The University of Melbourne, St Vincent's Hospital, Melbourne, Victoria, Australia. kate.wiggins@svhm.org.au
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pubmed:publicationType |
Journal Article
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