rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
3
|
pubmed:dateCreated |
1991-9-30
|
pubmed:databankReference |
|
pubmed:abstractText |
The cell division cycle gene CDC15 is essential for the late nuclear division in the yeast Saccharomyces cerevisiae. The amino acid sequence of the 974 amino acids/110 kDa CDC15 gene product, as deduced from the nucleotide sequence, includes an aminoterminal protein kinase domain which contains a primary sequence mosaic showing patterns specific for protein serine/threonine kinases besides those for protein tyrosine kinases. Many protein kinases non-essential for growth are known. CDC15 represents an essential protein kinase like CDC7 and CDC28. A carboxyterminal deletion of 32 amino acids renders the protein inactive.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0749-503X
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
7
|
pubmed:geneSymbol |
CDC15
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
265-73
|
pubmed:dateRevised |
2009-11-19
|
pubmed:meshHeading |
pubmed-meshheading:1882551-Amino Acid Sequence,
pubmed-meshheading:1882551-Base Sequence,
pubmed-meshheading:1882551-Cell Cycle,
pubmed-meshheading:1882551-DNA, Fungal,
pubmed-meshheading:1882551-Molecular Sequence Data,
pubmed-meshheading:1882551-Mutagenesis,
pubmed-meshheading:1882551-Open Reading Frames,
pubmed-meshheading:1882551-Plasmids,
pubmed-meshheading:1882551-Protein Kinases,
pubmed-meshheading:1882551-Restriction Mapping,
pubmed-meshheading:1882551-Saccharomyces cerevisiae,
pubmed-meshheading:1882551-TATA Box
|
pubmed:year |
1991
|
pubmed:articleTitle |
CDC15, an essential cell cycle gene in Saccharomyces cerevisiae, encodes a protein kinase domain.
|
pubmed:affiliation |
Institut für Mikro- und Molekularbiologie der Universität Giessen, F.R.G.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|