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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2009-1-9
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pubmed:databankReference |
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/EU430496,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/EU430497,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/EU430498,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/EU430499,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/EU430500,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/EU430501,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/EU430502,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/EU430503,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/EU430504,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/EU430505,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/EU430506,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/EU430507,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/EU430508,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/EU430509,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/EU430510,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/EU430511
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pubmed:abstractText |
Two avian influenza virus strains, A/domestic green-winged teal/Hunan/67/2005 (H5N1) (D-GWT/67) and A/domestic green-winged teal/Hunan/79/2005 (H5N1) (D-GWT/79), were isolated from healthy domestic green-winged teals (Anas crecca) in Hunan Province, South China. Genomic analysis showed that both isolates were reassortants. The hemagglutinin (HA) genes of the two isolates were closely related to that of an H5N1 strain isolated from tree sparrow (A/tree sparrow/Henan/1/04). The neuraminidase (NA) genes and the internal protein genes of both isolates were closely related to those from A/chicken/Shantou/4231/2003-like (H5N1) viruses, with exception of the matrix (M) gene of D-GWT/79, which was closely related to that of the H7N3 strain A/mallard/Netherlands/12/2000 isolated from wild mallard duck. The virulence of the two isolates was examined in chickens, ducks, and mice. Both strains were found to be highly pathogenic in chickens and ducks, but showed low pathogenicity in mice. These findings contribute to the realization that domestic green-winged teals carrying the H5N1 virus may play an important role in transmitting the virus among birds.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Hemagglutinin Glycoproteins...,
http://linkedlifedata.com/resource/pubmed/chemical/M1 protein, Influenza A virus,
http://linkedlifedata.com/resource/pubmed/chemical/NA protein, influenza A virus,
http://linkedlifedata.com/resource/pubmed/chemical/Neuraminidase,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Viral,
http://linkedlifedata.com/resource/pubmed/chemical/Viral Matrix Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Viral Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/hemagglutinin, avian influenza A...
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0920-8569
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
38
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
66-73
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pubmed:meshHeading |
pubmed-meshheading:18825495-Animals,
pubmed-meshheading:18825495-Anseriformes,
pubmed-meshheading:18825495-Chick Embryo,
pubmed-meshheading:18825495-Chickens,
pubmed-meshheading:18825495-China,
pubmed-meshheading:18825495-Ducks,
pubmed-meshheading:18825495-Female,
pubmed-meshheading:18825495-Hemagglutinin Glycoproteins, Influenza Virus,
pubmed-meshheading:18825495-Influenza A Virus, H5N1 Subtype,
pubmed-meshheading:18825495-Influenza in Birds,
pubmed-meshheading:18825495-Mice,
pubmed-meshheading:18825495-Mice, Inbred BALB C,
pubmed-meshheading:18825495-Molecular Sequence Data,
pubmed-meshheading:18825495-Neuraminidase,
pubmed-meshheading:18825495-Orthomyxoviridae Infections,
pubmed-meshheading:18825495-Phylogeny,
pubmed-meshheading:18825495-RNA, Viral,
pubmed-meshheading:18825495-Reassortant Viruses,
pubmed-meshheading:18825495-Sequence Analysis, DNA,
pubmed-meshheading:18825495-Sequence Homology,
pubmed-meshheading:18825495-Survival Analysis,
pubmed-meshheading:18825495-Viral Matrix Proteins,
pubmed-meshheading:18825495-Viral Proteins,
pubmed-meshheading:18825495-Virulence
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pubmed:year |
2009
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pubmed:articleTitle |
Characterization of H5N1 influenza A viruses isolated from domestic green-winged teal.
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pubmed:affiliation |
State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, 430071, Hubei, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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